3360-78-9

Basic information

• Product Name: N-(2-AMINO-4-METHOXYPHENYL)-N-METHYLAMINE
• Synonyms: N-(2-AMINO-4-METHOXYPHENYL)-N-METHYLAMINE;1,2-BenzenediaMine, 4-Methoxy-N1-Methyl-;4-Methoxy-1-N-Methylbenzene-1,2-diaMine;4-methoxy-N1-methylbenzene-1,2-diamine
• CAS NO: 3360-78-9
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.19
• Mol File: 3360-78-9.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 300.537 °C at 760 mmHg
• Flash Point: 135.56 °C
• Appearance: /
• Density: 1.126 g/cm³
• Vapor Pressure: 0.00111mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: N-(2-AMINO-4-METHOXYPHENYL)-N-METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-AMINO-4-METHOXYPHENYL)-N-METHYLAMINE(3360-78-9)
• EPA Substance Registry System: N-(2-AMINO-4-METHOXYPHENYL)-N-METHYLAMINE(3360-78-9)

Safety Data

• Hazardous Substances Data: 3360-78-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H12N2O/c1-10-8-4-3-6(11-2)5-7(8)9/h3-5,10H,9H2,1-2H3

Upstream product

• 3360-79-0 N-methyl-4-methoxy-2-nitroaniline 
• 96-96-8 4-methoxy-2-nitroaniline 
• 85122-54-9 3-nitro-4(benzotriazol-1-ylmethyl)aminoanisole 
• 61324-93-4 1-fluoro-nitro-4-methoxybenzene 
• 69397-93-9 N-methyl-5-methoxy-2-nitroaniline 
• 872312-31-7 N-methyl-N-tert-butoxycarbonyl-O-(4-methoxybenzoyl)hydroxylamine 

Downstream Products

• 50591-24-7 1,2-dimethyl-5-methoxybenzimidazole 
• 68426-83-5 (5-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methanol 
• 50591-22-5 1-methyl-1H-benzo[d]imidazol-5-ol 
• 10394-39-5 5-methoxy-1-methyl-1H-benzo[d]imidazole 
• 4583-86-2 5-methoxy-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one 
• 79759-30-1 5-methoxy-1-methyl-3-phenyl-1,3-dihydro-2H-benzo[d]imidazol-2-one 
• 213118-53-7 1-(2-Amino-4-methoxy-phenyl)-1,3-dimethyl-urea 
• 213118-54-8 1-(2-Amino-4-chloro-phenyl)-1,3-dimethyl-urea 
• 4600-29-7 5-Methoxy-N-methyl-2-phenyl-2,3-dihydro-1H-1,3,2-benzodiaza-phosphol-2-sulfid 

Relevant articles and documents

Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes

CuH-catalyzed intramolecular cyclization and intermolecular allylation of benzimidazoles with allenes have been described. The reaction proceeded smoothly with the catalytic system of Cu(OAc)2/Xantphos and catalytic amount of (MeO)2MeSiH. This protocol features mild reaction conditions and a good tolerance of substrates bearing electron-withdrawing, electron-donating, or electron-neutral groups. A new catalytic mechanism was proposed for this copper hydride catalytic system.

INHIBITORS OF VAP-1

Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.

ERBB RECEPTOR INHIBITORS

Disclosed are compounds inhibiting ErbBs (e. g. HER2), pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition can effectively treat diseases associated ErbBs (especially HER2), including cancer.