33611-63-1Relevant academic research and scientific papers
Base-Promoted Synthesis of O -Aryl/Alkyl N, N -Dimethylthiocarbamates Starting from Inexpensive and Environmentally Benign Disulfide
Dong, Zhi-Bing,Wang, Ming,Zhu, Hui,Liu, Xing,Chang, Cai-Zhu
, p. 5258 - 5262 (2017)
A series of O -aryl (alkyl) N, N -dimethylthiocarbamates were synthesized in good yields (70-77%) by reacting substituted phenols or alkyl alcohol with inexpensive, stable, and environmentally benign tetramethylthiuram disulfide (TMTD) in the presence of NaH. By avoiding use of the toxic and corrosive N, N -dialkylthiocarbamoyl chloride, the method provides a green and facile preparation for some important precursors of potentially biologically reactive compounds.
