33666-40-9

Upstream product

• 1428260-82-5 C₄H₅Cl₂I 
• 108-95-2 phenol 
• 3591-45-5 1-bromomethyl-2,2-dichlorocyclopropane 
• 15475-65-7 1,1-dichloro-2-methylenecyclopropane 
• 3722-05-2 2-(chloromethyl)-1,1-dichlorocyclopropane 
• 67-66-3 chloroform 
• 1746-13-0 allyl phenyl ether 
• 515-84-4 Ethyl trichloroacetate 

Downstream Products

• 1144042-73-8 1,1-bis(trimethylstannyl)-2-(phenyloxymethyl)cyclopropane 

Relevant academic research and scientific papers

Reactions of substituted gem-dichlorocyclopropanes with phenols

By studying the reactions of substituted phenols with halomethyl-gem- dichlorocyclopropanes in dimethyl sulfoxide, concurrent for both endocyclic and exocyclic chlorine atoms, it was found that cis- and trans-1,1,3-trichloro-2- (chloromethyl)cyclopropanes react with phenols, producing 1,1-disubstituted (chloromethylen)cyclopropanes, as mixtures of Z- and E-configuration isomers, and 1,1-disubstituted 2-chloro-3-methylencyclopropanes. Cyclopropane ring cleaving was observed in reactions of phenols with 2-bromo-2-phenylgem- dichlorocyclopropane. The nature of the nucleophile has a significant effect on the yield of the reaction products.

Two way reactivity of 1,1-dichloro-2-(chloromethyl)cyclopropane in basic medium: A simple synthesis of 1,1-bis(aryloxy)-2-methylenecyclopropanes

1,1-Dichloro-2-(chloromethyl)cyclopropane (1) reacts with phenols 2a-1, alcohols 2m,n or thiophenol (2o) in different base/solvent systems, to form either 2-(aryloxymethyl)-1,1-dichlorocyclopropanes 3 and/or 1,1-bis(aryloxy)-2-methylenecyclopropanes 4. Re

A NEW REACTION OF 1,1-DICHLORO-2-HALOMETHYLCYCLOPROPANES IN BASIC MEDIUM

Utilization of nucleophilic reagents with 1b allows for the simple preparation of methylenecyclopropane derivatives 3 via elimination-addition routes.