N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester is a complex organic compound with the molecular formula C21H27NO7. It is a derivative of L-glutamic acid, an essential amino acid, and is characterized by the presence of a benzyloxycarbonyl group (Cbz) protecting the N-terminus of the glycine residue. The diethyl ester group indicates that the carboxylic acid groups of the glutamic acid are esterified with ethanol. N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester is often used in peptide synthesis as a protected amino acid building block, where the Cbz group serves to protect the amino group from unwanted side reactions during the coupling process. The diethyl ester group can be hydrolyzed under acidic conditions to regenerate the free carboxylic acid, allowing for further reactions or purification steps. N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester is crucial in the synthesis of peptides and proteins, particularly in solid-phase peptide synthesis (SPPS), where the protecting groups are strategically removed to allow for the stepwise addition of amino acids to form the desired peptide sequence.
3369-03-7
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Basic information
- Product Name: N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester
- Synonyms:
- CAS NO:3369-03-7
- Molecular Formula:
- Molecular Weight: 394.425
- EINECS: N/A
- Product Categories: N/A
- Mol File: 3369-03-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester(3369-03-7)
- EPA Substance Registry System: N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester(3369-03-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3369-03-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3369-03-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,6 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.Calculate Digit Verification of CAS Registry Number 3369-03:
(6*3)+(5*3)+(4*6)+(3*9)+(2*0)+(1*3)=87
87 % 10 = 7
So 3369-03-7 is a valid CAS Registry Number.
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N-(N-benzyloxycarbonyl-glycyl)-L-glutamic acid diethyl ester
