33691-09-7

Basic information

• Product Name: Benzeneacetic acid, 4-chloro-.alpha.-forMyl-, ethyl ester
• Synonyms: Benzeneacetic acid, 4-chloro-.alpha.-forMyl-, ethyl ester;4-Chloro-alpha-formylbenzeneacetic acid ethyl ester;Ethyl 2-(4-chlorophenyl)-3-oxopropanoate;ethyl 2-(4-chlorophenyl)-2-formylacetate;ethyl α-formyl-4-chlorophenylacetate
• CAS NO: 33691-09-7
• Molecular Formula: C₁₁H₁₁ClO₃
• Molecular Weight: 226.65624
• Mol File: 33691-09-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 49-51℃
• Boiling Point: 143-145℃ (8 Torr)
• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, 4-chloro-.alpha.-forMyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 4-chloro-.alpha.-forMyl-, ethyl ester(33691-09-7)
• EPA Substance Registry System: Benzeneacetic acid, 4-chloro-.alpha.-forMyl-, ethyl ester(33691-09-7)

Safety Data

• Hazardous Substances Data: 33691-09-7(Hazardous Substances Data)

Usage

General Description

Benzeneacetic acid, 4-chloro-.alpha.-formyl-, ethyl ester is a chemical compound often used in the field of organic chemistry as a reagent or intermediate in broader chemical reactions. Structurally, it is derived from benzeneacetic acid, with one hydrogen atom replaced by a chlorine atom and an alpha-formyl group. The presence of an ethyl ester function enhances its reactivity, allowing it to participate in numerous reactions. While it has wide applications in science and industry, it's important to note that direct physical contact or inhalation should be avoided, as exposure can potentially cause irritation and other health hazards. The handling, storage, and disposal of this chemical should follow established safety protocols.

Upstream product

• 14062-24-9 4-chloro-benzeneacetic acid, ethyl ester 
• 109-94-4 formic acid ethyl ester 
• 7476-81-5 p-chlorophenyl butanoate 
• 1878-66-6 4-chlorophenylacetic Acid 

Downstream Products

• 15937-29-8 3-ethoxy-2-(4-chloro-phenyl)-acrylic acid ethyl ester 
• 1078133-75-1 C₂₄H₂₀Br₂ClNO₃ 
• 1078133-65-9 C₂₄H₂₀Br₂ClNO₃ 
• 1078133-90-0 C₂₀H₂₀ClNO₂ 
• 1078133-79-5 C₁₇H₁₅ClFNO₂ 
• 1078133-69-3 C₁₇H₁₅ClFNO₂ 
• 1078133-82-0 C₁₇H₁₄Br₂ClNO₂ 
• 1078133-72-8 C₁₇H₁₄Br₂ClNO₂ 
• 1078133-81-9 C₁₇H₁₄ClF₂NO₂ 
• 1078133-71-7 (Z)-ethyl 2-(4-chlorophenyl)-3-(2,4-difluorophenyl-amino)acrylate 
• 1078133-77-3 C₁₇H₁₄Br₂ClNO₃ 
• 1078133-67-1 C₁₇H₁₄Br₂ClNO₃ 

Relevant articles and documents

PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS

The present invention relates to a process for the preparation of a compound of formula (I), wherein R1 is as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.

Lewis base catalyzed asymmetric hydrosilylation of α-substituted β-enamino esters: Facile access to enantioenriched β2-amino esters via dynamic kinetic resolution

A chiral Lewis base organocatalyzed asymmetric hydrosilylation of α-substituted β-enamino esters is presented. The reactions proceeded through dynamic kinetic resolution to afford various enantioenriched β2-amino esters with high yields (up to

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials

A series of potential antimicrobial derivatives possessing bioisosteric replacements for the central oxazolidinone ring found in oxazolidinone antibacterials have been prepared. The design concept involved replacement of the requisite sp3-hybridized stereogenic center found at the 5-position of the oxazolidinone with a nitrogen atom. The synthesis and antibacterial activity of three such ring systems, the benzisoxazolinones, pyrroles, and isoxazolinones is described.