33696-06-9

Upstream product

• 98-88-4 benzoyl chloride 
• 100-83-4 meta-hydroxybenzaldehyde 
• 87199-16-4 3-Formylphenylboronic acid 
• 65-85-0 benzoic acid 
• 10533-83-2 N-benzoyl-N-methyl-4-methylbenzenesulfonamide 
• 101137-69-3 tert-butyl benzoyl(phenyl)carbamate 
• 81912-53-0 4(S)-(methoxycarbonyl)-N-benzoyl-1,3-oxazolidine-2-thione 
• 81925-64-6 methyl 3-benzoyl-2-thioxothiazolidine-4-carboxylate 

Downstream Products

• 620-18-8 3-hydroxystyrene 
• 867179-03-1 3-benzoyloxy-trans-cinnamic acid 
• 116324-77-7 4-(3-Benzoyloxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester 
• 298704-01-5 3-Benzoyloxybenzaldehyde dimethyl acetal 
• 65-85-0 benzoic acid 
• 121445-45-2 [(3-hydroxyphenyl)methoxymethylene]tricyclo[3.3.1.13.7]-decane 
• 298704-04-8 Dimethyl 1-methoxy-1-(3-benzoyloxyphenyl)methylphosphonate 
• 10401-11-3 3-hydroxy phenylacetylene 
• 10401-10-2 3-(3-hydroxyphenyl)-2-propynoic acid 
• 1174021-76-1 C₂₆H₂₇NO₆ 
• 613-90-1 benzoyl cyanide 
• 98568-87-7 C₇H₅O₂^(1-)*K⁽¹⁺⁾ 

Relevant academic research and scientific papers

Metal-Free Selective Modification of Secondary Amides: Application in Late-Stage Diversification of Peptides

Here we solve a long-standing challenge of the site-selective modification of secondary amides and present a simple two-step, metal-free approach to selectively modify a particular secondary amide in molecules containing multiple primary and secondary amides. Density functional theory (DFT) provides insight into the activation of C-N bonds. This study encompasses distinct chemical advances for late-stage modification of peptides thus harnessing the amides for the incorporation of various functional groups into natural and synthetic molecules.

A specific and selective chemiluminescent probe for Pd2+ detection

As an important transition metal catalyst, palladium is extensively used in many areas including electronics industry, petroleum industry, automobile industry and fine chemicals engineering. However, it brings harm to the environment as well as people's h

Transition-Metal-Free Esterification of Amides via Selective N-C Cleavage under Mild Conditions

A general, transition-metal-free, and operationally simple method for esterification of amides by a highly selective cleavage of N-C(O) bonds under exceedingly mild conditions is reported. The reaction is characterized by broad substrate scope and excellent functional group tolerance. The potential of this mild esterification is highlighted by late-stage diversification of natural products and pharmaceuticals. Conceptually, the metal-free acyl functionalization of amides represents a significant step forward as a practical alternative to ligand exchange in acylmetal intermediates.

A chemiluminescence sensor with signal amplification based on a self-immolative reaction for the detection of fluoride ion at low concentrations

A sensory system incorporated with an amplification function was developed for the detection of trace-level fluoride ions. This sensory system comprises two steps: amplification and chemiluminescence. These steps were linked with chemical reactions and we

A sensitive and selective chemiluminogenic probe for palladium

Palladium triggered removal of a propargyl group leads to the cleavage of the 1,2-dioxetane ring, leading to bright chemiluminescence. The reaction of the probe is highly specific for the Pd species, thus the probe described here has considerable potentia

Metal-free synthesis of aryl esters by coupling aryl carboxylic acids and aryl boronic acids

A facile synthesis of aryl esters is developed by coupling aryl carboxylic acids and aryl boronic acids in the presence of PhI(OAc)2 and carbonyl diimidazole. A wide range of functional groups were tolerant to the metal-free reaction condition that led to the desired products in good yields.

Chemiluminescence sensing of fluoride ions using a self-immolative amplifier

An enhanced chemiluminescence signal is obtained when electronically triggered dioxetane cleavage is initiated by fluoride-mediated deprotection of the silyl-protecting group, followed by self-immolation via 1,4-quinone-methide rearrangement. The reaction

Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones

A number of mono- or diaminoalkylated indeno[1,2-c]isoquinolin-5,11-diones analogs of 1 were synthesized and evaluated for their DNA binding affinities, topoisomerase inhibition properties and antiproliferative activities against human cancer cell lines (

Kinetics and mechanism of nucleophilic displacement reactions of Y-substituted phenyl benzoates with cyanide Ion

Second-order rate constants (kCN-) have been measured for nucleophilic substitution reactions of Y-substituted phenyl benzoates (1a-r) with CN- ion in 80 mol % H2O/20 mol % DMSO at 25.0 ± 0.1 °C. The Bronsted-type plot is linear with βlg = -0.49, a typical βlg value for reactions reported to proceed through a concerted mechanism. Hammett plots correlated with σo and σ-constants exhibit many scattered points. In contrast, the Yukawa-Tsuno plot for the same reaction exhibits excellent linearity with pY = 1.37 and r = 0.34, indicating that a negative charge develops partially on the oxygen atom of the leaving aryloxide in the rate-determining step (RDS). Although two different mechanisms are plausible (i.e., a concerted mechanism and a stepwise pathway in which expulsion of the leaving group occurs at the RDS), the reaction has been concluded to proceed through a concerted mechanism on the basis of the magnitude of βlg and pY values.

Aminolysis of 2,4-dinitrophenyl X-substituted benzoates and Y-substituted phenyl benzoates in MeCN: Effect of the reaction medium on rate and mechanism

Second-order rate constants (kN) have been determined spectrophotometrically for the reactions of 2,4-di-nitrophenyl X-substituted benzoates (1a-f) and Y-substituted phenyl benzoates (2a-h) with a series of alicyclic secondary amines in MeCN at