337-20-2

Basic information

• Product Name: PERFLUORO-2-BUTANONE
• Synonyms: OCTAFLUORO-2-BUTANONE;OCTAFLUOROBUTAN-2-ONE;PERFLUORO-2-BUTANONE;OCTAFLUORO-2-BUTANONE, PRESSURE TIN;Octafluorobutan-2-one, 1,1,1,3,3,4,4,4-Octafluorobutan-2-one;Perfluorobutan-2-one;Octafluoro-2-butanone >=97%
• CAS NO: 337-20-2
• Molecular Formula: C₄F₈O
• Molecular Weight: 216.03
• Product Categories: Alkyl Fluorinated Building Blocks;Building Blocks;C3 to C6;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Ketones;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks
• Mol File: 337-20-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: −126 °C(lit.)
• Boiling Point: 0 °C
• Appearance: /
• Density: 1.595g/cm³
• Vapor Pressure: 785mmHg at 25°C
• Refractive Index: 1.255
• CAS DataBase Reference: PERFLUORO-2-BUTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUORO-2-BUTANONE(337-20-2)
• EPA Substance Registry System: PERFLUORO-2-BUTANONE(337-20-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1956 2.2
• WGK Germany: 3
• F: 4.5-21-31
• HazardClass: 2.3
• Hazardous Substances Data: 337-20-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 337-20-2 differently. You can refer to the following data:
1. Reactant involved in synthesis of 2,3-bis(perfluoroalkyl)quinoxalines1
2. Reactant involved in synthesis of 2,3-bis(perfluoroalkyl)quinoxalines

InChI:InChI=1/C4F8O/c5-2(6,4(10,11)12)1(13)3(7,8)9

Upstream product

• 344336-22-7 perfluoro-3-methyl-2,3-epoxypentane 
• 773-29-5 trans/cis-octafluoro-2,3-epoxybutane 
• 95-54-5 1,2-diamino-benzene 
• 95-55-6 2-amino-phenol 
• 93830-84-3 perfluoro-3,4-dimethyl-3,4-epoxyhexane 

Downstream Products

• 354-33-6 1,1,1,2,2-pentafluoroethane 
• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

Reactions of epoxides derived from internal perfluoroolefins with o-phenylenediamine and 2-aminophenol

The reactions of epoxy derivatives of internal perfluoroolefins with o-phenylenediamine and 2-aminophenol in dioxane gave 23-67% of the corresponding 2,3-bis(perfluoroalkyl)quinoxalines and 2,3-bis-(perfluoroalkyl)-2H-1,4- benzoxazin-2-ols, respectively. When N,N-dimethylacetamide was used as a solvent, the main reaction pathway was anionic isomerization of epoxides into ketones which were then converted into 2-perfluoroalkylbenzimidazoles (in the reactions with o-phenylenediamine) or 2-hydroxy-N-perfluoroalkanoylanilines (in the reactions with 2-aminophenol). The reaction of 3,4-epoxydodecafluorohexane with 2-aminophenol in N,N-dimethylacetamide was accompanied by unusual cyclization to afford 2-pentafluoropropanoyl-2-pentafluoroethyl-1,3- benzoxazolidine. Pleiades Publishing, Inc., 2006.

Reactions Involving Fluoride Ion. Part 30. Preparation and Reactions of Epoxides Derived from Perfluoroalkyl Substituted Alkenes

Reactions of alkenes that are oligomers of tetrafluoroethene or hexafluorocyclobutene with sodium hypochlorite give epoxides which show remarkable overall stability.Ring-opening reactions, induced by fluoride ion, yield alkenes, ketones, and acid fluorides.