33709-29-4

Usage

Preparation

Preparation by reaction of aluminium chloride on gallacetophenone trimethyl ether in refluxing chlorobenzene (71%).

InChI:InChI=1/C8H8O4/c1-4(9)5-2-6(10)8(12)7(11)3-5/h2-3,10-12H,1H3

Upstream product

• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 
• 2887-72-1 1-(3,5-dibromo-4-hydroxyphenyl)ethan-1-one 
• 99-93-4 4-Hydroxyacetophenone 
• 2478-38-8 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone 
• 51863-60-6 3,5-dihydroxyacetophenone 

Downstream Products

• 896121-38-3 3,4,5-tribenzyloxyphenylmethyl ketone 

Relevant academic research and scientific papers

Enhancing the Antioxidant Activity of Technical Lignins by Combining Solvent Fractionation and Ionic-Liquid Treatment

A grass soda technical lignin (PB1000) underwent a process combining solvent fractionation and treatment with an ionic liquid (IL), and a comprehensive investigation of the structural modifications was performed by using high-performance size-exclusion ch

Iron-catalyzed arene C-H hydroxylation

The sustainable, undirected, and selective catalytic hydroxylation of arenes remains an ongoing research challenge because of the relative inertness of aryl carbon-hydrogen bonds, the higher reactivity of the phenolic products leading to over-oxidized by-products, and the frequently insufficient regioselectivity. We report that iron coordinated by a bioinspired L-cystine-derived ligand can catalyze undirected arene carbon-hydrogen hydroxylation with hydrogen peroxide as the terminal oxidant. The reaction is distinguished by its broad substrate scope, excellent selectivity, and good yields, and it showcases compatibility with oxidation-sensitive functional groups, such as alcohols, polyphenols, aldehydes, and even a boronic acid. This method is well suited for the synthesis of polyphenols through multiple carbon-hydrogen hydroxylations, as well as the late-stage functionalization of natural products and drug molecules.

Studies towards the synthesis of 13C-labelled anthocyanins

The anthocyanins are a class of polyphenols found in nature, which are widely distributed throughout the plant kingdom and are thought to possess antioxidant properties. Methodology previously developed in our group for the regioselective placement of 13C-atoms into aromatic rings is being applied to the synthesis of 13C-labelled anthocyanins-namely cyanidin-3-glucoside and delphinidin-3-glucoside. Copyright

Method for dyeing keratinous fibres using a monohydroxyindole or dihydroxyindole and a non-oxidizing aromatic carbonyl derivative and dyeing agent

The present invention relates to a method for dyeing keratinous fibers, characterized in that the following are applied to the fibers: a) a composition (A) containing, in a medium appropriate for dyeing, at least one monohydroxyindole or dihydroxyindole, this application being preceded or followed by the application of b) a composition (B) containing, in a medium appropriate for dyeing, at least one aromatic carbonyl derivative chosen from hydroxyacetophenones, hydroxybenzophenones, 2-hydroxy-1,4-benzoquinones, hydroxy-1,4-naphthoquinones,amino-1,4-naphthoquinones,hydroxy-9,10-anthraquinones and amino-9,10-anthraquinones. It also relates to the dyeing agents for carrying it out.

Intermediates useful for the synthesis of delphinidin chloride

A process is provided for producing delphinidin which comprises reacting a compound of formula STR1 wherein each Pg represents a hydroxyl protecting group, and Lg represents a leaving group with a compound of formula STR2 wherein Pg' represents a hydroxyl protecting group characterized in that the compound of formula VII is produced from an intermediate of formula STR3 wherein each Pg" represents a hydroxyl protecting group and each Alk represents lower alkyl, by (i) subjecting the intermediate of formula IX to hydrolysis and decarboxylation to form 3,4,5-trihydroxyacetophenone of formula STR4 (ii) converting the 3,4,5-trihydroxyacetophenone to the compound of formula VII by introduction of the protecting groups Pg" and converting the group of formula --COCH3 to a group of formula --COCH2 Lg.