33713-02-9Relevant academic research and scientific papers
Orally active zwitterionic factor Xa inhibitors with long duration of action
Mochizuki, Akiyoshi,Nagata, Tsutomu,Kanno, Hideyuki,Takano, Daisuke,Kishida, Masamichi,Suzuki, Makoto,Ohta, Toshiharu
, p. 7337 - 7343 (2012/02/04)
We have optimized 2-aminomethylphenylamine derivative as a factor Xa inhibitor. Several polar functional groups were introduced in the central phenyl ring, and we focused on zwitter ionic compound showing continuous inhibitory activity in oral administrat
PROLYL HYDROXYLASE INHIBITORS
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Page/Page column 26; 28, (2010/07/10)
The invention described herein relates to certain 2,4-dioxo-l,2,3,4-tetrahydro-7- quinazolinecarboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
