125229-13-2Relevant articles and documents
Development of a flexible strategy towards FR900482 and the mitomycins
Trost, Barry M.,O'Boyle, Brendan M.,Torres, Wildeliz,Ameriks, Michael K.
supporting information; experimental part, p. 7890 - 7903 (2011/08/06)
FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and obvious structural similarity. Both classes possess potent anticancer activity, a feature that has led to their investigation
PROLYL HYDROXYLASE INHIBITORS
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Page/Page column 26-28, (2010/07/10)
The invention described herein relates to certain 2,4-dioxo-l,2,3,4-tetrahydro-7- quinazolinecarboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
Enantiospecific synthesis of an aziridinobenzoazocinone, an advanced intermediate containing the core nucleus of FR900482 and FK973
Jones,Rapoport
, p. 1144 - 1146 (2007/10/02)
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