33721-54-9

Basic information

• Product Name: N-(2-methoxy-5-nitrophenyl)acetamide
• Synonyms: N-(2-methoxy-5-nitrophenyl)acetamide;2'-Methoxy-5'-nitroacetanilide
• CAS NO: 33721-54-9
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.1867
• EINECS: 251-656-1
• Mol File: 33721-54-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 392.6°Cat760mmHg
• Flash Point: 191.2°C
• Appearance: /
• Density: 1.327g/cm³
• Vapor Pressure: 2.26E-06mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: N-(2-methoxy-5-nitrophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methoxy-5-nitrophenyl)acetamide(33721-54-9)
• EPA Substance Registry System: N-(2-methoxy-5-nitrophenyl)acetamide(33721-54-9)

Safety Data

• Hazardous Substances Data: 33721-54-9(Hazardous Substances Data)

Usage

General Description

N-(2-methoxy-5-nitrophenyl)acetamide is a chemical compound composed of a nitro group, a methoxy group, and an amide group attached to a phenyl ring. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. The presence of the nitro and methoxy groups makes it useful in medicinal chemistry, as these groups can have significant effects on the biological activity of the resulting compounds. N-(2-methoxy-5-nitrophenyl)acetamide may be used in the development of drugs for conditions such as cancer, bacterial infections, and inflammation. Additionally, it has potential applications in the field of organic chemistry for the synthesis of complex molecules.

InChI:InChI=1/C9H10N2O4/c1-6(12)10-8-5-7(11(13)14)3-4-9(8)15-2/h3-5H,1-2H3,(H,10,12)

Upstream product

• 93-26-5 2-methoxyacetanilide 
• 7697-37-2 nitric acid 
• 108-24-7 acetic anhydride 
• 67827-72-9 2-methoxy-5-nitroaniline hydrochloride 
• 99-59-2 3-amino-4-methoxynitrobenzene 
• 64-19-7 acetic acid 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 119-27-7 2,4-dinitroanisole 
• 90-04-0 2-methoxy-phenylamine 
• 7664-93-9 sulfuric acid 
• 74-83-9 methyl bromide 
• 97-60-9 2-acetamido-4-nitrophenol 

Downstream Products

• 64353-88-4 N-(5-amino-2-methoxyphenyl)-acetamide 
• 79127-57-4 4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid 
• 72909-34-3 pyrroloquinoline quinone 
• 953392-39-7 N₁-[5-({[3-fluoro-4-(5-methyl-2-furanyl)phenyl]sulfonyl}amino)-2-(methyloxy)phenyl]-2-methylalaninamide hydrochloride 
• 953391-99-6 1,1-dimethylethyl (2-{[5-({[3-fluoro-4-(5-methyl-2-furanyl)phenyl]sulfonyl}amino)-2-(methyloxy)phenyl]amino}-1,1-dimethyl-2-oxoethyl)carbamate 
• 953391-97-4 N-[5-({[3-fluoro-4-(5-methyl-2-furanyl)phenyl]sulfonyl}amino)-2-(methyloxy)phenyl]acetamide 
• 953391-98-5 N-[3-amino-4-(methyloxy)phenyl]-3-fluoro-4-(5-methyl-2-furanyl)benzenesulfonamide 
• 953391-96-3 N-[5-{[(4-bromo-3-fluorophenyl)sulfonyl]amino}-2-(methyloxy)phenyl]acetamide 
• 15854-75-8 2-methoxy-5-nitro-1,1’-biphenyl 
• 20278-59-5 4,5-dinitro-2-methoxyaniline 
• 188630-75-3 N-(5-methanesulfonamido-2-methoxy)phenylacetamide 
• 91573-25-0 2-methoxy-5-nitro-diacetanilide 
• 15854-76-9 2-Methoxy-5-nitro-N-nitroso-acetanilid 

Relevant articles and documents

4,5-disubstituted-1-hydro-pyrrole(2,3-f)quinoline-2,7,9-tricarboxylate compound and application

The invention discloses a 4,5-disubstituted-1-hydro-pyrrole(2,3-f)quinoline-2,7,9-tricarboxylate compound and analogues or derivatives thereof. The structure of the compound is shown as a formula I, and the structural formula is as shown in the specification. In the formula, R1 and R4 are respectively and independently selected from the following atoms or groups: hydrogen, linear or branched C1-8 alkyl, deuterated linear or branched C1-8 alkyl, aralkyl or substituted aryl radical; R2 is independently selected from the following atoms or groups: halogen, linear or branched C1-8 alkoxy and deuterated linear or branched C1-8 alkoxy; and R3 is independently selected from the following atoms or groups: linear or branched C1-8 alkoxy and deuterated linear or branched C1-8 alkoxy. The compound can serve as a reaction intermediate for synthesizing PQQ (Pyrroloquinoline Quinone), and the oxidizing agent process adopting CAN in the PQQ synthesis in the conventional patent and literature is replaced. Therefore, the whole process is cheap and high-efficiency.

ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS

The present invention therefore provides compounds of formula (I) or pharmaceutically acceptable salts thereof: (I) processes for their preparation, pharmaceutical compositions containing the same and to their use in the treatment of gastrointestinal and other disorders.

TRICYCLIC PROTEIN KINASE INHIBITORS

This invention provides compounds of Formula (I), where A'', Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.