337308-91-5Relevant academic research and scientific papers
Synthesis of bone-targeted oestrogenic compounds for the inhibition of bone resorption
Bulman Page, Philip C,Moore, Jonathan P.G,Mansfield, Ian,McKenzie, Michael J,Bowler, Wayne B,Gallagher, James A
, p. 1837 - 1847 (2007/10/03)
Syntheses have been realised for several members of a new class of potential bone resorption inhibitors consisting of steroidal oestrogenic compounds linked at the 17 position to a geminal bis(phosphonic acid) moiety through an ester linkage. The approach used has the potential to allow other biologically active compounds to be coupled to the geminal bisphosphonate unit.
