33738-83-9Relevant academic research and scientific papers
A novel synthesis of 3,4-disubstituted cinnolines from o- trifluorophenyl hydrazones
Kiselyov, Alexander S.,Dominguez, Celia
, p. 5111 - 5114 (1999)
An efficient synthesis of 3-aryl-4-aminocinnolines from ortho- trifluoromethylphenyl hydrazones is described. The mechanism of the described transformation is likely to involve the formation of the quinone methide intermediate. The described procedure is
BF3-Etherate-Promoted Cascade Reaction of 2-Alkynylanilines with Nitriles: One-Pot Assembly of 4-Amido-Cinnolines
Senadi, Gopal Chandru,Gore, Babasaheb Sopan,Hu, Wan-Ping,Wang, Jeh-Jeng
, p. 2890 - 2893 (2016/07/06)
A BF3-etherate-promoted cascade reaction of nitriles with 2-alkynylanilines is described. This method achieves the formation of two new C-N bonds through a reaction sequence of diazotization with t-BuONO, nucleophilic addition of the alkyne to
