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N-benzyl-tert-butylamine hydrochloride is a chemical compound with the molecular formula C14H22ClN. It is a white crystalline solid that is soluble in water and various organic solvents. N-benzyl-tert-butylamine hydrochloride is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also employed as a reagent in organic synthesis, particularly in the preparation of amines and other nitrogen-containing compounds. The hydrochloride salt form of the compound enhances its stability and solubility, making it a preferred form for many applications.

3378-81-2

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3378-81-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3378-81-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,7 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3378-81:
(6*3)+(5*3)+(4*7)+(3*8)+(2*8)+(1*1)=102
102 % 10 = 2
So 3378-81-2 is a valid CAS Registry Number.

3378-81-2Downstream Products

3378-81-2Relevant academic research and scientific papers

A Manganese Nanosheet: New Cluster Topology and Catalysis

Chakraborty, Uttam,Reyes-Rodriguez, Efrain,Demeshko, Serhiy,Meyer, Franc,Jacobi von Wangelin, Axel

, p. 4970 - 4975 (2018)

While the coordination chemistry of monometallic complexes and the surface characteristics of larger metal particles are well understood, preparations of molecular metallic nanoclusters remain a great challenge. Discrete planar metal clusters constitute nanoscale snapshots of cluster growth but are especially rare owing to the strong preference for three-dimensional structures and rapid aggregation or decomposition. A simple ligand-exchange procedure has led to the formation of a novel heteroleptic Mn6 nanocluster that crystallized in an unprecedented flat-chair topology and exhibited unique magnetic and catalytic properties. Magnetic susceptibility studies documented strong electronic communication between the manganese ions. Reductive activation of the molecular Mn6 cluster enabled catalytic hydrogenations of alkenes, alkynes, and imines.

Expanding Coefficient: A Parameter to Assess the Stability of Induced-Fit Complexes

Talotta, Carmen,Concilio, Gerardo,De Rosa, Margherita,Soriente, Annunziata,Gaeta, Carmine,Rescifina, Antonio,Ballester, Pablo,Neri, Placido

supporting information, p. 1804 - 1808 (2021/03/08)

Here we propose a new parameter, the Expanding Coefficient (EC), that can be correlated with the thermodynamic stability of supramolecular complexes governed by weak secondary interactions and obeying the induced-fit model. The EC values show a good linear relationship with the log Kapp of the respective pseudorotaxane complexes investigated. According to Cram's Principle of Preorganization, the EC can be considered an approximate mechanical measure of the host's reorganization energy cost upon adopting the final bound geometry.

The N-Substitution of Aliphatic Primary Amines via 1-benzotriazoles: Preparation of Secondary Amines

Katritzky, Alan R.,Glen, Noble,Pilarski, Boguslaw,Harris, Philip

, p. 1443 - 1446 (2007/10/02)

A new method has been developed for the selective conversion of primary aliphatic amines into unsymmetrical secondary amines by Grignard reaction of 1-benzotriazoles 1.This method employs simple procedures and mild conditions, and is specific in that onyl monoalkylation of the primary amines results.

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