33809-30-2

Upstream product

• 64936-41-0 4-tert-butyl-1-(hydroxy(phenyl)methyl)-1-cyclohexene 
• 934-56-5 trimethyl(phenyl)stannane 
• 77412-96-5 1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 98-07-7 Benzotrichlorid 
• 201230-82-2 carbon monoxide 
• 100-52-7 benzaldehyde 
• 455-32-3 benzoyl fluoride 

Relevant academic research and scientific papers

Enones from Acid Fluorides and Vinyl Triflates by Reductive Nickel Catalysis

A nickel-catalyzed reductive coupling between acid fluorides and vinyl triflates has been described. This method provides an efficient access to various enones and avoids the requirement for acyl or vinyl metallic reagents in the conventional approaches.

1,2-Addition of α,α,α-trichlorotoluene to ketones via a Mg Barbier reaction in DMF: New route to cycloalk-1-en-1-yl and alk-1-en-1-yl phenyl ketones

The reductive cyclocondensation of α,α,α-trichlorotoluene to enolisable ketones enables the preparation of (cyclo)alken-1-en-1-yl phenyl ketones via the formation of an intermediate chlorooxirane. Copyright Taylor & Francis Group, LLC.

Palladium-catalyzed carbonylative coupling reactions using triorganoindium compounds

A novel palladium-catalyzed carbonylative cross-coupling reaction that employs triorganoindium compounds is described. The reaction proceeds under a carbon monoxide atmosphere with alkyl-, alkynyl-, and arylindium reagents to give good yields of unsymmetrical ketones with high atom economy. All three organic groups attached to the metal are efficiently transferred in this carbonylative coupling reaction.

Cathodic Addition of Benzylidyne Trichloride to Ketones and Aldehydes

Ketones are converted to homologated enones 7a-g in good yields by cathodic addition of benzylidyne trichloride (1d).As intermediates α-Chlorooxiranes 6 are assumed, which rearrange via α-keto carbenium ions 9 to enones.The intermediacy of 9 is supported by the addition of 1d to norcamphor, where the products indicate equilibrating norbornyl cations as intermediates. α,β-Unsaturated ketones lead depending on steric shielding of the double bond to the cyclopropane 23 as 1,4-adduct or the enone 26 as 1,2-adduct.With aldehydes and 1d, α-chloro or βhydroxy ketones, the conversion products of 2-chlorooxiranes, are obtained.

DESHYDROGENATION D'ALCOOLS EN COMPOSES CARBONYLES PAR LE SYSTEME CuCl/O2/Ligande

The dehydrogenation of alcohols to the corresponding carbonyl compounds by CuCl/O2/ligand (L) shows relative rates of dehydrogenation according to the type of alcohol used; primary or secondary benzyl alcohols>allylic alcohols or aliphatic alcohols>cyclic alcohols.The rate of this reaction was found to be dependent upon the nature of the ligands used; e.g. phenanthroline 1-10>bipyridyl 2,2'>TMEDA, etc.When L=phenanthroline 1-10 the catalytic effect, of the system ROH/CuCl/L (3:1:1), was found to be similar to the system ROH/CuCl/L (1:2:2).The pure oxygen was replaced by air without any noticeable change in the rate of the reaction.The primary aliphatic alcohols lead to the aldehydes containing 1, 2, etc. carbon atoms fewer than the starting alcohols.