338385-72-1

Upstream product

• 338385-70-9 (4S,5S)-5-[(R)-(tert-Butyl-dimethyl-silanyloxy)-phenyl-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 623-47-2 propynoic acid ethyl ester 
• 338385-68-5 (4S)-4-t-butyldimethylsilyloxy-4-phenyl-2S,3S-O-isopropylidene-butyl benzyl ether 
• 338385-66-3 (4S)-4-hydroxy-4-phenyl-2S,3S-O-isopropylidene-butyl benzyl ether 
• 214678-52-1 {(4R,5S)-5-[(R)-{[(tert-butyl)(dimethyl)silyl]oxy}(phenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}methanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 81801-09-4 4-O-benzyl-2,3-O-isopropylidene-D-threose 

Downstream Products

• 1211548-20-7 C₃₃H₄₂O₇Si 
• 338385-77-6 ethyl 7S-t-butyldimethylsilyloxy-7-phenyl-5S,6S-O-isopropylidene-4S-methoxymethyl-hepten-2Z-oate 
• 338385-75-4 ethyl 7S-t-butyldimethylsilyloxy-7-phenyl-5S,6S-O-isopropylidene-4S-methoxymethyl-heptyn-2-oate 

Relevant academic research and scientific papers

First total synthesis of (+)-crassalactone A

A simple and highly efficient first total synthesis of cytotoxic (+)-crassalactone A starting from (R)-mandelic acid is described. The strategy involves the osmium tetroxide-catalyzed cis-hydroxylation and the stereoselective addition of ethyl lithiopropi

Total synthesis of four diastereoisomers of Goniofufurone from D-(-)- or L-(+)-tartaric acid

(+) and (-)-Goniofufurones, (+) and (-)-8-epi-goniofufurones have been synthesized from D-(-) and L-(+)-tartaric acids by the addition of ethyl lithiopropiolate to a chiral aldehyde intermediate as a key step, in which LDA is the best base compared to n-BuLi plus Lewis acid YCl3 (cat.).