33842-18-1

Basic information

• Product Name: Methyl 6-broMobenzo[d][1,3]dioxole-4-carboxylate
• Synonyms: Methyl 6-broMobenzo[d][1,3]dioxole-4-carboxylate
• CAS NO: 33842-18-1
• Molecular Formula: C9H7BrO4
• Molecular Weight: 259.05348
• Mol File: 33842-18-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 6-broMobenzo[d][1,3]dioxole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 6-broMobenzo[d][1,3]dioxole-4-carboxylate(33842-18-1)
• EPA Substance Registry System: Methyl 6-broMobenzo[d][1,3]dioxole-4-carboxylate(33842-18-1)

Safety Data

• Hazardous Substances Data: 33842-18-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 6-bromobenzo[d][1,3]dioxole-4-carboxylate is used as a key intermediate in the synthesis of various pharmaceuticals for its potential biological activities. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, methyl 6-bromobenzo[d][1,3]dioxole-4-carboxylate is utilized as a building block in the creation of novel agrochemicals. Its incorporation into these compounds can lead to the development of more effective and targeted pest control solutions, enhancing agricultural productivity and crop protection.
Used in Organic Chemistry Research:
Methyl 6-bromobenzo[d][1,3]dioxole-4-carboxylate is employed as a versatile intermediate in organic chemistry for exploring new reaction pathways and synthesizing complex organic compounds. Its reactivity and structural features make it a valuable tool for researchers in the field, facilitating the discovery of new compounds with diverse applications.
Used in Chemical Reactions and Processes:
Methyl 6-bromobenzo[d][1,3]dioxole-4-carboxylate may also be used in various chemical reactions and processes to produce more complex compounds with desirable properties and applications. Its involvement in these reactions can lead to the creation of new materials with specific characteristics, broadening the scope of chemical and material science.

Upstream product

• 33842-16-9 benzo[1,3]dioxole-4-carboxylic acid methyl ester 
• 2411-83-8 methyl-2,3-dihydroxybenzoate 
• 105603-49-4 methyl 5-bromo-2,3-dihydroxybenzoate 
• 74-95-3 1,1-dibromomethane 
• 303-38-8 2,3-Dihydroxybenzoic acid 
• 72517-15-8 2,3-dihydroxy-5-bromobenzoic acid 

Relevant articles and documents

New geldanamycin derivatives with anti Hsp properties by mutasynthesis

Mutasynthetic supplementation of the AHBA blocked mutant strain of S. hygroscopicus, the geldanamycin producer, with 21 aromatic and heteroaromatic amino acids provided new nonquinoid geldanamycin derivatives. Large scale (5 L) fermentation provided four new derivatives in sufficient quantity for full structural characterisation. Among these, the first thiophene derivative of reblastatin showed strong antiproliferative activity towards several human cancer cell lines. Additionally, inhibitory effects on human heat shock protein Hsp90α and bacterial heat shock protein from H. pylori HpHtpG were observed, revealing strong displacement properties for labelled ATP and demonstrating that the ATP-binding site of Hsps is the target site for the new geldanamycin derivatives.

C-GLUCOSIDE DERIVATIVE CONTAINING FUSED PHENYL RING OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present disclosure relates to C-glycoside derivatives having a fused phenyl ring or pharmaceutical acceptable salts thereof, a method for preparing the same, a pharmaceutical composition comprising the same, a use thereof and a method for dual inhibition of SGLT1 and SGLT2 using the same. A novel compound of the present disclosure has a dual inhibitory activity against SGLT1 and SGLT2, thus being valuably used as a diabetes therapeutic agent.