338422-68-7 Usage
Type of compound
Heterocyclic compound It contains a ring structure with atoms of different elements, specifically a pyrazole ring.
Structure
Pyrazole ring The compound has a five-membered ring with one nitrogen atom and one oxygen atom in the ring, giving it the general structure of a pyrazole.
Substituents
4-methoxyphenyl and trifluoromethyl The pyrazole ring has a 4-methoxyphenyl group (an aromatic ring with a methoxy substituent) at position 2 and a trifluoromethyl group (a carbon atom bonded to three fluorine atoms) at position 5.
Application
Pharmaceutical industry 2-(4-methoxyphenyl)-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one is used as a building block for the synthesis of various pharmaceutical drugs.
Biological activity
Exhibits biological activity The compound has been observed to interact with biological systems, which is important for its potential therapeutic applications.
Therapeutic potential
Being studied for potential therapeutic applications Researchers are investigating the possible uses of 2-(4-methoxyphenyl)-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one in the development of new medications.
Importance in research and development
Valuable for medicinal chemistry The unique structure and properties of 2-(4-methoxyphenyl)-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one make it an important subject for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 338422-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,8,4,2 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 338422-68:
(8*3)+(7*3)+(6*8)+(5*4)+(4*2)+(3*2)+(2*6)+(1*8)=147
147 % 10 = 7
So 338422-68-7 is a valid CAS Registry Number.
338422-68-7Relevant academic research and scientific papers
Sheng, Xiao,Hua, Kai,Yang, Chunyu,Wang, Xiaoli,Ji, Hui,Xu, Jinyi,Huang, Zhangjian,Zhang, Yihua
, p. 3535 - 3540 (2015)
Abstract Fourteen hybrids (10a-g, 11a-g) of 3-n-butylphthalide (NBP) and edaravone (Eda) analogues have been designed and synthesized as potential anti-ischemic stroke agents. In vitro biological studies showed that compounds 10d and 10g exhibited more potent anti-platelet aggregation than ticlopidine (Ticlid), aspirin (ASP) and NBP. Compound 10g more significantly prevented H2O2-mediated neuronal cell (PC12) death than NBP, Eda or NBP together with Eda. Meanwhile, 10g also possessed potent radical scavenging effects on hydroxyl radical (·OH) and superoxide anion radical (·O2-). Our findings may provide new insights into the development of these hybrids, like 10g, for the intervention of ischemic stroke.
