36993-97-2

Upstream product

• 15969-31-0 5-Amino-6-phenyl-1,2,4-triazine 
• 61788-14-5 3-hydrazino-6-phenyl-1,2,4-triazine-5(4H)-one 
• 113978-50-0 5-oxo-6-phenyl-4,5-dihydro-[1,2,4]triazine-3-carboxylic acid 
• 103754-70-7 5-amino-6-phenyl-[1,2,4]triazine-3-carboxylic acid 
• 190711-23-0 5-cyano-6-phenyl-1,2,4-triazine 
• 33859-68-6 6-Phenyl-1,2,4-triazine N-oxide 
• 308276-74-6 5-cyanoimino-6-phenyl-2,5-dihydro-1,2,4-triazine 
• 110513-70-7 chloro-[(cyano-phenyl-methylene)-hydrazono]-acetic acid methyl ester 
• 110972-75-3 4-nitroso-5-phenyl-1⁽²⁾H-pyrazole-3-carboxylic acid methyl ester 
• 20577-73-5 methyl 4-phenyl-2,4-dioxobutanoate 

Downstream Products

• 1252017-92-7 (S)-2-[(S)-3-methyl-2-tosylaminobutanoyl]-3-(1H-indol-3-yl)-6-phenyl-3,4-dihydro-1,2,4-triazin-5(2H)-one 
• 1105709-22-5 3-(1H-indol-3-yl)-2-[2-(6-methoxynaphthalen-2-yl)propionyl]-6-phenyl-3,4-dihydro-2H-[1,2,4]triazin-5-one 
• 1105709-21-4 ethyl 3-(1H-indol-3-yl)-5-oxo-6-phenyl-4,5-dihydro-3H-[1,2,4]triazine-2-carboxylate 
• 1262053-85-9 (S)-2-[(S)-4-methyl-2-tosylaminopentanoyl]-3-(1-methyl-1H-pyrrol-3-yl)-6-phenyl-3,4-dihydro-1,2,4-triazin-5(2H)-one 
• 1262053-82-6 (S)-2-[(S)-4-methyl-2-tosylaminopentanoyl]-3-(1H-indol-3-yl)-6-phenyl-3,4-dihydro-1,2,4-triazin-5(2H)-one 
• 1262053-68-8 2,4-diacetyl-3-(1H-indol-3-yl)-6-phenyl-3,4-dihydro-2H-[1,2,4]triazin-5-one 
• 1262053-70-2 2,4-diacetyl-3-(2-methyl-1H-indol-3-yl)-6-phenyl-3,4-dihydro-2H-[1,2,4]triazin-5-one 
• 1262053-69-9 2,4-diacetyl-3-(1-methyl-1H-indol-3-yl)-6-phenyl-3,4-dihydro-2H-[1,2,4]triazin-5-one 

Relevant academic research and scientific papers

Asymmetric induction in the reactions of azinones with C-nucleophiles

Effect of acylating agents on the course of addition of C-nucleophiles to 1,2,4- and 1,3,5-triazinones, as well as to quinoxalin-2(1H)-one, was studied. A series of new azinone derivatives was obtained. A method for the preparation of diastereomerically pure addition products of indoles to 1,2,4-triazinones and quinoxalin-2(1H)-one in the presence of N-Ts-L-amino acid acyl chlorides was suggested.

Nucleophilic substitution of hydrogen in the reaction of 1,2,4-triazin-4-oxides with cyanamide

It was shown that cyanamide can successfully be used in reactions of nucleophilic substitution of hydrogen with 1,2,4-triazin-4-oxides in the presence of a base to give 5-cyanoimino-1,2,4-triazines. It was found by 13C NMR spectroscopy that these compounds and their alkylalion products at the cyclic nitrogen atom exist in the form of 5-cyanoimino-2,5-dihydro-1,2,4-triazines.