338969-77-0Relevant academic research and scientific papers
6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists
Isaac, Methvin,Slassi, Abdelmalik,Xin, Tao,MacLean, Neil,Wilson, Julie,McCallum, Kirk,Wang, Hong,Demchyshyn, Lidia
, p. 1719 - 1721 (2000)
A novel series of 6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives was synthesized and found to be potent and selective 5-HT6 receptor antagonists. (C) 2000 Elsevier Science Ltd. All rights reserved.
6' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY
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Page/Page column 39; 40, (2008/12/08)
The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1—R4 A, B, D, E, and G are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
