339008-49-0

Usage

Uses

Used in Organic Synthesis:
(4-Chlorophenyl)-(6-chloropyridazin-3-yl)-acetonitrile is used as a synthetic intermediate for the development of complex organic molecules. Its unique structure allows for further functionalization and incorporation into larger molecular frameworks.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4-Chlorophenyl)-(6-chloropyridazin-3-yl)-acetonitrile is used as a potential lead compound for the design and synthesis of new drugs. Its structural features may contribute to the development of therapeutic agents with novel mechanisms of action.
Used in Agrochemicals:
(4-Chlorophenyl)-(6-chloropyridazin-3-yl)-acetonitrile may also find applications in the agrochemical sector as a potential active ingredient in pesticides or herbicides. Its chemical properties could be harnessed to target specific pests or weeds, improving crop protection strategies.

Upstream product

• 141-30-0 3,6-dichlorpyridazine 
• 140-53-4 p-chlorobenzyl cyanide 

Downstream Products

• 1159497-56-9 2-(4-chlorophenyl)-2-(6-morpholinopyridazin-3-yl)acetonitrile 
• 1159497-62-7 2-(4-chlorophenyl)-2-(6-chloropyridazin-3-yl)acetamide 
• 1159497-80-9 C₁₂H₁₀ClN₃S₂ 
• 1159497-82-1 C₁₂H₉Cl₂N₃S 
• 1159497-58-1 2-(4-chlorophenyl)-2-[6-(4-phenylpiperazin-1-yl)pyridazin-3-yl]acetonitrile 
• 1159497-57-0 2-[6-(4-benzylpiperidin-1-yl)pyridazin-3-yl]-2-(4-chlorophenyl)acetonitrile 
• 303997-39-9 2-(4-chlorophenyl)-2-[6-(phenylthio)pyridazin-3-yl]acetonitrile 
• 1159497-64-9 2-(4-chlorophenyl)-2-[6-(4-phenylpiperazin-1-yl)pyridazin-3-yl]acetamide 
• 1159497-63-8 2-[6-(4-benzylpiperidin-1-yl)pyridazin-3-yl]-2-(4-chlorophenyl)acetamide 

Relevant academic research and scientific papers

Microwave-enhanced efficient synthesis of some polyfunctional pyridazines

Microwave-enhanced highly efficient protocol for the synthesis of polyfunctional pyridazines beginning from 3,6-dichloropyridazine in environmentally benign ionic liquids have been developed. The products obtained were 3-amino-6-chloropyridazine, 3,6-diaminopyridazine, and 3-chloro-6- methoxypyridazine. These derivatives were then be converted to a variety of polyfunctional pyridazine derivatives. The ionic liquids used were 1-n-butyl-3-methylimidazolium hydroxide/tetrafluoroborate/hexafluorophosphate and 1,3-di-n-butylimidazolium hydroxide. This powerful strategy is less time-consuming green methodology. The ionic liquid employed may be recovered and recycled.

Synthesis, fungicidal and antibacterial activity of new pyridazine derivatives

Compounds 1-3 were obtained in the reaction of 3,6-dichloro-pyridazines with phenylacetonitriles in the biphasic system - DMSO/50% NaOH. The chlorine atom was replaced with cycloalkylamino (4-13) and hydrazinyl (23, 24) moiety. These last compounds were condensed with aldehydes (25-34). Pyridazynylphenylacetonitriles were converted into amides 14-18 and thioamides 19-22. In compounds 2, 3 the chlorine atom was replaced with thiophenyl (37, 38) and in compound 1 with thioethyl and thiophenyl (35, 36) functional groups. In the reactions of compounds 1, 2 with ammonium polysulfide thioamides with thiol group (39, 40) and chlorine atom (41, 42) were obtained. Compounds 1-17, 19-43 were screened for antibacterial and fungicidal activities.