33905-47-4

Basic information

• Product Name: Ethanol, 2-[phenyl(phenylmethyl)amino]-
• CAS NO: 33905-47-4
• Molecular Formula: C15H17NO
• Molecular Weight: 227.306
• Mol File: 33905-47-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Ethanol, 2-[phenyl(phenylmethyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-[phenyl(phenylmethyl)amino]-(33905-47-4)
• EPA Substance Registry System: Ethanol, 2-[phenyl(phenylmethyl)amino]-(33905-47-4)

Safety Data

• Hazardous Substances Data: 33905-47-4(Hazardous Substances Data)

Upstream product

• 758640-21-0 N-Benzylaniline 
• 107-21-1 ethylene glycol 
• 540-51-2 2-bromoethanol 
• 87-72-9 D-Xylose 
• 1426958-04-4 4,4,5,5-tetramethyl-N-phenyl-N-(phenylmethyl)-1,3,2-dioxaborolan-2-amine 
• 56-81-5 glycerol 
• 62-53-3 aniline 
• 122-98-5 2-Anilinoethanol 
• 87100-28-5 pinacol benzylboronate 
• 100-44-7 benzyl chloride 

Downstream Products

• 961-71-7 Antergan 
• 109388-15-0 methyl cis-1,2-diphenylpyrrolidine-3-carboxylate 
• 51-50-3 N,N-dibenzyl-2-chloroethanamine 
• 109651-07-2 1-(N,N-dibenzylamino)-2-iodoethane 
• 128194-11-6 (S)-2-ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-1-methoxymethyl-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate 

Relevant articles and documents

Aza-Matteson Reactions via Controlled Mono-and Double-Methylene Insertions into Nitrogen-Boron Bonds

Boron-homologation reactions represent an efficient and programmable approach to prepare alkylboronates, which are valuable and versatile synthetic intermediates. The typical boron-homologation reaction, also known as the Matteson reaction, involves formal carbenoid insertions into C-B bonds. Here we report the development of aza-Matteson reactions via carbenoid insertions into the N-B bonds of aminoboranes. By changing the leaving groups of the carbenoids and altering Lewis acid activators, selective mono- and double-methylene insertions can be realized to access various α- and β-boron-substituted tertiary amines, respectively, from common secondary amines. The derivatization of complex amine-containing bioactive molecules, diverse functionalization of the boronate products, and sequential insertions of different carbenoids have also been achieved.

Direct hydroxyethylation of amines by carbohydrates: Via ruthenium catalysis

An efficient and halogen-free catalytic methodology for the synthesis of β-amino alcohols from aromatic amines and biomass-derived carbohydrates is demonstrated for the first time. The activation of C5/C6 sugars by a ruthenium catalyst selectively generates the C2 alkylating reagent glycolaldehyde. The transformation involves metal-catalyzed hydrogen borrowing for the reduction of the imine intermediate. A series of arylamines bearing various substituents were successfully transformed into the desired products in good to excellent yields.

Copper-catalyzed N- and O-alkylation of amines and phenols using alkylborane reagents

By the reaction of amines with alkylborane reagents in the presence of a catalytic amount of copper(II) acetate Cu(OAc)2 and di-tert-butyl peroxide, a cross-coupling reaction proceeded and alkylated amines were obtained in good to excellent yields. Phenols are also applicable for this reaction, and the corresponding alkyl aryl ethers were produced.