961-71-7 Usage
History
In 1942 phenbenzamine (Antergan), C17H22N2, was the first antihistamine to be successfully used in humans.
Reactivity Profile
Antergan neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Safety Profile
Poison by subcutaneous,intraperitoneal, and intramuscular routes. When heated todecomposition it emits toxic fumes of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 961-71-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,6 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 961-71:
(5*9)+(4*6)+(3*1)+(2*7)+(1*1)=87
87 % 10 = 7
So 961-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H22N2/c1-18(2)13-14-19(17-11-7-4-8-12-17)15-16-9-5-3-6-10-16/h3-12H,13-15H2,1-2H3
961-71-7Relevant articles and documents
Dimethylamination of Primary Alcohols Using a Homogeneous Iridium Catalyst: A Synthetic Method for N, N-Dimethylamine Derivatives
Jeong, Jaeyoung,Fujita, Ken-Ichi
, p. 4053 - 4060 (2021/03/09)
A new catalytic system for N,N-dimethylamination of primary alcohols using aqueous dimethylamine in the absence of additional organic solvents has been developed. The reaction proceeds via borrowing hydrogen processes, which are atom-efficient and environmentally benign. An iridium catalyst bearing an N-heterocyclic carbene (NHC) ligand exhibited high performance, without showing any deactivation under aqueous conditions. In addition, valuable N,N-dimethylamine derivatives, including biologically active and pharmaceutical molecules, were synthesized. The practical application of this methodology was demonstrated by a gram-scale reaction.
Oxydation biometic of the antergan to the iodylbenzene
Barret,Pautet,Daudon
, p. 132 - 132 (2007/10/02)
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