33942-49-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(carbamothioylamino)benzoic acid is used as a pharmaceutical compound for its potential therapeutic applications in the treatment of various diseases. Its antimicrobial and antifungal properties make it a candidate for developing new drugs to combat infections.
Used in Medicinal Chemistry Research:
2-(carbamothioylamino)benzoic acid is used as a research compound in medicinal chemistry for exploring its pharmacological properties and potential applications in drug discovery. Its unique chemical structure allows scientists to investigate its interactions with biological targets and evaluate its efficacy in treating specific conditions.
Used in Antimicrobial Applications:
2-(carbamothioylamino)benzoic acid is used as an antimicrobial agent for its ability to inhibit the growth of microorganisms, such as bacteria and fungi. This makes it a potential candidate for developing new antibiotics and antifungal medications to address the increasing problem of drug resistance.
Used in Drug Delivery Systems:
2-(carbamothioylamino)benzoic acid can be used in the development of drug delivery systems to improve the bioavailability and therapeutic outcomes of medications. Its chemical properties may allow for the creation of novel carriers or formulations that enhance the effectiveness of drugs in treating various diseases.

Upstream product

• 13277-24-2 N-benzoyl-N'-(2-carboxyphenyl)thiourea 
• 1147550-11-5 ammonium thiocyanate 
• 118-92-3 anthranilic acid 

Downstream Products

• 19573-79-6 2-(4-oxo-4,5-dihydro-thiazol-2-ylamino)-benzoic acid 
• 37182-79-9 N-(4-phenyl-thiazol-2-yl)-anthranilic acid 
• 101716-74-9 N-(4-trans-styryl-thiazol-2-yl)-anthranilic acid 
• 82844-29-9 2-[4,4-Bis-(2-hydroxy-phenyl)-5-oxo-2-thioxo-imidazolidin-1-yl]-benzoic acid 
• 134241-00-2 2-acetylamino-4H-3,1-benzothiazin-4-one 
• 19573-79-6 2-(4-oxo-thiazolidin-2-ylideneamino)benzoic acid 
• 82844-41-5 2-[4,4-Bis-(4-hydroxy-phenyl)-5-oxo-2-thioxo-imidazolidin-1-yl]-benzoic acid 
• 13906-09-7 2-mercapto-3,4-dihydro-4-quinazolone 
• 87634-34-2 N-cyanoanthranilic acid 
• 116433-30-8 C₃₂H₂₈N₆O₈S₃ 

Relevant academic research and scientific papers

Synthesis, Characterization and Antibacterial Activity of Some Transition Metal Complexes with Thiourea Derivatives

Transition metal complexes of Mn(II), Co(II) and Ni(II) ions with 2-hydroxyphenylthiourea, 2-carboxyphenylthiourea and 4-methyl-phenylthiourea have been synthesized and characterized on the basis of elemental analyses, conductivity and magnetic measurements and from their IR spectral studies.The complexes have the general formula: K22-)2(NO3)2>, L2 = Dinegative deprotonated form of the ligand, 2-hydroxyphenylthiourea; , where L = 4-methylphenylthiourea and -)2(NO3)2>, where L- = Uni-negative deprotonated form of the ligand, 2-carboxyphenylthiourea, with 2-hydroxyphenylthiourea and 2-carboxyphenylthiourea, Mn(II), Co(II) and Ni(II) metal ions form 5-coordinate bridging complexes whereas 4-methylphenylthiourea gives rise to 4-coordinated complexes with the same metal ions.The antibacterial activity of the ligands and their complexes have been tested with Bacillus subtilis.Some complexes show higher activity then that of the free ligand value whereas in some cases the activity decreases.Some complexes were found to retain the same activity as that of the ligand. - Key Words: Metal complexes; Thiourea ligands; Antibacterial activity.

REACTIONS OF N-BENZOYL ISOTHIOCYANATE WITH ANTHRANILIC ACID AND METHYL ANTHRANILATE

N-Benzoyl-N'-(2-carboxy- and -2-methoxycarbonylphenyl)thioureas have been obtained by the reaction of N-benzoyl isothiocyanate with anthranilic acid and methyl anthranilate, respectively.Kinetics of cyclization of these compounds into 2-mercapto-3,4-dihydro-4-quinazolone have been studied in water and in methanol.In the base-catalyzed cyclization of N-benzoyl-N'-(2-carboxyphenyl)thiourea the proper cyclization is preceded by solvolysis of the benzoyl group.In the case of N-benzoyl-N'-(2-methoxycarbonylphenyl)thiourea the reaction rate is limited by the base-catalyzed cyclization of the starting benzoyl derivative; the benzoyl group is split off in a subsequent rapid step.