33948-93-5

Upstream product

• 120-72-9 indole 
• 99-61-6 3-nitro-benzaldehyde 
• 19865-57-7 3-nitro-benzaldehyde-(N-phenyl oxime ) 
• 123-11-5 4-methoxy-benzaldehyde 
• 5676-82-4 (3-nitrobenzylidene)aniline 
• 7539-23-3 1-(3-nitrobenzylidene)-2-phenylhydrazine 
• 121-89-1 3-Nitroacetophenone 
• 52670-38-9 2-ethynylaniline 
• 615-43-0 2-iodophenylamine 
• 73845-02-0 4-methyl-N-(3-nitrobenzylidene)benzenesulfonamide 

Downstream Products

• 1124380-68-2 C₂₉H₁₉N₄O₆P 
• 1124380-65-9 C₂₅H₂₀N₃O₃PS 
• 1124380-63-7 C₂₉H₂₀N₃O₂PSe 
• 1124380-67-1 C₂₉H₂₀N₃O₄P 

Relevant academic research and scientific papers

3-Amino-5-mercapto-1,2,4-triazole-functionalized Fe3O4 magnetic nanocomposite as a green and efficient catalyst for synthesis of bis(indolyl)methane derivatives

A core–shell Fe3O4?silica magnetic nanocomposite functionalized with 3-amino-5-mercapto-1,2,4-triazole (Fe3O4/SiO2/PTS/AMTA) was prepared using Fe3O4 with silica layer, and its s

A new bismuth nitrate-catalyzed electrophilic substitution of indoles with carbonyl compounds under solvent-free conditions

An expeditious synthetic method for the preparation of bis(indollyl)methane derivatives has been developed through a bismuth nitrate-catalyzed reaction of indole with various carbonyl compounds in mortar and pastle under solvent-free conditions. Copyright

Cis-Dioxido-molybdenum(VI) complexes of tridentate ONO hydrazone Schiff base: Synthesis, characterization, X-ray crystal structure, DFT calculation and catalytic activity

Two new cis-MoO2 [MoO2(L)(EtOH)] (1), [MoO2(L)(Py)] (2) [L: (3-methoxy-2oxidobenzylidene)benzohydrazidato], complexes have been synthesized and fully characterized on the basis of elemental analysis, FT-IR, molar conductiv

An efficient procedure for the preparation of mono, and di-bis-indolyl methanes catalyzed by molibdatophosphoric acid

H3PMo12O40·xH2O was found to be an effective catalyst for the preparation of bis-indolyl derivatives from indole and aromatic, aliphatic, heterocyclic aldehydes or ketones in ethanol at room temperature.

Halogen bond-catalyzed friedel-crafts alkylation of indole with ketones and aldehydes for the synthesis of symmetrical 3,3’-diindolylmethanes using simple halogen donor catalyst

The Friedel-Crafts alkylation of indole with ketones and aldehydes had been developed to prepare 3,3’-diindolylmethanes using iodine or NCS as catalysts. Two mild and efficient catalysis systems were provided for the activation of carbonyl compounds and i

Air-stable μ-oxo-bridged binuclear titanium(IV) salophen perfluorooctanesulfonate as a highly efficient and recyclable catalyst for the synthesis of bis(indolyl) methane derivatives

An air-stable μ-oxo-bridged binuclear Lewis acid of titanium(IV) salophen perfluorooctanesulfonate [{Ti(salophen)H2O}2O][OSO2C8F17]2 (1) was successfully synthesized by the reaction of TiIV(salophen)Cl2 with AgOSO2C8F17 and characterized by different techniques such as IR, NMR and HRMS. TG-DSC analysis showed that this complex was thermally stable at 220 °C. Meanwhile, it exhibited good solubility in polar organic solvents and good ionic dissociation in CH3CN solution. Fluorescence spectra and Hammett indicator results indicated that the complex had relatively strong acidity. And it showed high catalytic efficiency for the synthesis of bis(indolyl) methane derivatives through Friedel-crafts reaction of aldehyde/ketone with indoles. Moreover, it can be reused five times with minimal changes in catalytic efficiency.

Simple iodoalkyne-based organocatalysts for the activation of carbonyl compounds

A novel approach for the formation of bisindolylmethane derivatives (BIMs) is described as a proof of concept to evaluate the catalytic capacity of iodoalkynes. The use of these derivatives is reported as an example of simple halogen bond-based organocatalyst. This kind of activation has not been used before for the synthesis of bisindolylmethane derivatives 3. Interestingly, the preparation of 3-(1H-indol-3-yl)-1-phenylbutan-1-one (8) has been also achieved for the first time with an iodoalkyne derivative. We prove the efficiency of this family of new catalysts by developing a simple and easy operational methodology, opening the door to the development of alternative catalysts in the area of halogen bond-based organocatalysts.

Synthesis and Catalytic Application of Bimetallic and Trimetallic Magnetic Nanoalloys for the Preparation of Bis(indolyl)methanes

Abstract: Some bimetallic and trimetallic magnetic nanoalloys based on cobalt, copper,and silver have been synthesized and used as and green catalysts for thepreparation of bis(indolyl)methanes through electrophilic substitution reactionof indole with car

Heterogeneous SO3H@Fe3O4 magnetic nanocatalyst as an efficient and reusable medium for the synthesis of 3,3′-(arylmethylene)-bis-(4-hydroxycoumarin), bis-(indolyl)-methane, and 1,8-dioxo-octahydroxanthene derivatives

This work aimed to synthesize a new heterogeneous catalyst (SO3H@Fe3O4 magnetic nanoparticles) and the study of its catalytic behavior in synthesizing 3,3′-(arylmethylene)-bis-(4-hydroxycoumarin), bis-(indolyl)-methane, an

First Aminocatalytic Synthesis of Bis(indolyl)methanes and DFT Studies on the Reaction Pathway

Abstract: Carbon–carbon bond-formation by aminocatalytic nucleophilic addition to aryl aldehyde ideally generates addition–elimination product. Here, we report an unexpected, yet efficient aminocatalytic nucleophilic addition of indole to aryl aldehydes t