73845-02-0Relevant articles and documents
One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight
Ibert, Quentin,Cauwel, Madeleine,Glachet, Thomas,Tite, Tony,Le Nahenec-Martel, Patricia,Lohier, Jean-Fran?ois,Renard, Pierre-Yves,Franck, Xavier,Reboul, Vincent,Sabot, Cyrille
supporting information, p. 4390 - 4398 (2021/08/03)
Broad scope one-pot diazirine synthesis strategies have been developed using two different oxidants depending on the nature of the starting material. In all cases, an inexpensive commercial solution of ammonia (NH3) in methanol (MeOH) was emplo
Facile synthesis, antimicrobial and antiviral evaluation of novel substituted phenyl 1,3-thiazolidin-4-one sulfonyl derivatives
Mandal, Milan Kumar,Ghosh, Swagatika,Naesens, Lieve,Bhat, Hans Raj,Singh, Udaya Pratap
, (2021/07/17)
A series of novel substituted phenyl 1, 3-thiazolidin-4-one sulfonyl derivatives 5 (a-t) were synthesized and screened for their in-vitro anti-microbial and anti-viral activity. The result of the anti-microbial assay demonstrated compounds 5d, 5f, 5g, 5h,
Mild Darzens Annulations for the Assembly of Trifluoromethylthiolated (SCF3) Aziridine and Cyclopropane Structures
Delost, Michael D.,Njardarson, Jon T.
supporting information, p. 6121 - 6125 (2021/08/16)
We report mild new annulation approaches to trisubstituted trifluoromethylthiolated (SCF3) aziridines and cyclopropanes via Darzens inspired protocols. The products of these anionic annulations, rarely studied previously, possess attractive features rendering them valuable building blocks for synthesis platforms. In this study, trisubstituted acetophenone nucleophiles bearing SCF3 and bromine substituents in their α position were shown to undergo [2 + 1] annulations with vinyl ketones and tosyl-protected imines under mild reaction conditions.
Synthesis and biological evaluation of substituted phenyl azetidine-2-one sulphonyl derivatives as potential antimicrobial and antiviral agents
Mandal, Milan Kumar,Ghosh, Swagatika,Bhat, Hans Raj,Naesens, Lieve,Singh, Udaya Pratap
, (2020/10/12)
In the present study, we intend to synthesize a series of novel substituted phenyl azetidine-2-one sulphonyl derivatives. The entire set of derivatives 5 (a-t) were screened for in-vitro antibacterial, and antifungal activity, and among them eleven compou
Synthesis and histamine H3 and H4 receptor activity of conformationally restricted cyanoguanidines related to UR-PI376
Geyer, Roland,Buschauer, Armin
scheme or table, p. 775 - 785 (2012/03/12)
Recently, we identified highly potent agonists of the human histamine H4 receptor (hH4R) among a series of imidazolylbutylcyanoguanidines. Aiming at improved selectivity for the hH 4R relative to the H3 receptor
The first example of saccharin-lithium bromide catalysis: Direct synthesis of N-tosylimines from alcohols
Patel, Rajesh,Srivastava, Vishnu P.,Yadav, La Dhar S.
experimental part, p. 1610 - 1614 (2010/09/05)
The first procedure to access N-tosylimines directly from alcohols under mild and neutral conditions is reported. The protocol involves saccharin-lithium bromide-catalyzed oxidation of alcohols to aldehydes/ketones with chloramine-T followed by their condensation with the in situ generated oxidation by-product p-toluenesulfonamide in the same reaction vessel to afford N-tosylimines in 40-90% overall yields. The present work opens up a new and efficient synthetic route to N-tosyimines directly from alcohols in a one-pot procedure.
Preparation of N-arylsulfonyl imines from sulfonamides and aryl aldehydes using magnesium oxide as a heterogeneous and reusable catalyst under solvent-free conditions
Hasaninejad, Alireza,Zare, Abdolkarim,Zare, Ahmad Reza Moosavi,Parhami, Abolfath,Sharghi, Hashem,Khalafi-Nezhad, Ali
experimental part, p. 2769 - 2776 (2009/09/06)
An efficient solvent-free procedure for the preparation of N-arylsulfonyl imines from sulfonamides and aryl aldehydes in the presence of a catalytic amount of magnesium oxide and tetrabutylammonium bromide (TBAB) under microwave irradiation is described. The advantages of this method are good to high yields, short reaction times, low cost, and matching with green chemistry protocols. Copyright Taylor & Francis Group, LLC.
Practical and general entry to N-tosyl aryl aldimines promoted by sulfamic acid in water and alcohol
Li, Zhenjiang,Ren, Xinhua,Shi, Yuhu,Ouyang, Pingkai
, p. 713 - 724 (2007/10/03)
A practical, indirect procedure composed of a three-component condensation using aromatic aldehydes, p-tosylamide, and sodium p-toluenesulfinate in the presence of sulfamic acid in tap water-alcohol solvents to afford amidosulfones, and the subsequent wat
Efficient and convenient procedure for preparation of N-sulfonylimines catalyzed by montmorillonite K-10
Jin, Tong-Shou,Yu, Mi-Jun,Liu, Li-Bin,Zhao, Ying,Li, Tong-Shuang
, p. 2339 - 2344 (2007/10/03)
A general and practical chemical route to the synthesis of N-sulfonylimines using montmorillonite K-10 as the catalyst is described. This method provides several advantages such as operational simplicity, short reaction time, using of inexpensive materials, noncorrosivity, lack of pollution, and high yields. Copyright Taylor & Francis Group, LLC.