3395-03-7Relevant academic research and scientific papers
Radially Oriented [ n]Cyclo- meta-phenylenes
Castro, Edison,Mirzaei, Saber,Hernández Sánchez, Raúl
supporting information, p. 87 - 92 (2021/01/09)
Molecular compounds with zigzag carbon nanotube geometries are exceedingly rare. Here we report the synthesis and characterization of carbon-based nanotubes with zigzag geometry, best described as radially oriented [n]cyclo-meta-phenylenes, extending the tubularene family of compounds. By the incorporation of edge-sharing benzene rings into the tubularene's radial π-surface, we have uncovered the first step to give rise to the emergence of radial orbital distribution in zigzag nanorings.
The Synthesis of Hexaazatrinaphthylene-Based 2D Conjugated Copper Metal-Organic Framework for Highly Selective and Stable Electroreduction of CO2 to Methane
Dai, Lu,Li, Jiani,Li, Pengfei,Li, Shuai,Liu, Yanze,Lv, Jianning,Wang, Bo,Yin, Anxiang,Zhu, Zhejiaji
supporting information, p. 16409 - 16415 (2021/06/27)
2D conjugated MOFs have attracted significant interests in recent years owing to their special structural features and promising physical and chemical properties. These intriguing attributes, to a large extent, stem from the nature of incorporated ligands
Robust Photocatalytic Method Using Ethylene-Bridged Flavinium Salts for the Aerobic Oxidation of Unactivated Benzylic Substrates
Pokluda, Adam,Anwar, Zubair,Boguschová, Veronika,Anusiewicz, Iwona,Skurski, Piotr,Sikorski, Marek,Cibulka, Radek
supporting information, p. 4371 - 4379 (2021/04/02)
7,8-Dimethoxy-3-methyl-1,10-ethylenealloxazinium chloride (1a) was found to be a superior photooxidation catalyst among substituted ethylene-bridged flavinium salts (R=7,8-diMeO, 7,8-OCH2O-, 7,8-diMe, H, 7,8-diCl, 7-CF3 and 8-CF3). Selection was carried out based on structure vs catalytic activity and properties relationship investigations. Flavinium salt 1a proved to be robust enough for practical applications in benzylic oxidations/oxygenations, which was demonstrated using a series of substrates with high oxidation potential, i. e., 1-phenylethanol, ethylbenzene, diphenylmethane and diphenylmethanol derivatives substituted with electron-withdrawing groups (Cl or CF3). The unique capabilities of 1a can be attributed to its high photostability and participation via a relatively long-lived singlet excited state, which was confirmed using spectroscopic studies, electrochemical measurements and TD-DFT calculations. This allows the maximum use of the oxidation power of 1a, which is given by its singlet excited state reduction potential of +2.4 V. 7,8-Dichloro-3-methyl-1,10-ethylenealloxazinium chloride (1 h) can be used as an alternative photocatalyst for even more difficult substrates. (Figure presented.).
Polyhydroxy compound as well as preparation method and application thereof
-
Paragraph 0065-0069, (2021/10/27)
The invention relates to the technical field of metal organic framework materials, in particular to a polyhydroxy compound as well as a preparation method and application thereof. The invention discloses a polyhydroxy compound which contains 2 D π conjuga
A2-A1-D-A1-A2 type non-fullerene acceptors based on methoxy substituted benzotriazole with three different end-capped groups for P3HT-based organic solar cells
Zhang, Qianqian,Xiao, Bo,Du, Mengzhen,Li, Gongqiang,Tang, Ailing,Zhou, Erjun
supporting information, p. 10902 - 10909 (2018/10/25)
In the last three years, the A2-A1-D-A1-A2 skeleton has become increasingly popular in the design of non-fullerene acceptors (NFAs), and it could match particularly well with the classic p-type polymer of poly(3
Novel Aryl-Modified Benzoylamino-N-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-heteroamides as Potent Inhibitors of Vascular Endothelial Growth Factor Receptors 1 and 2
Ashok, Abhishek,Thanukrishnan, Kannan,Bhojya Naik, Halehatty S.,Maridu, Rajendraswami
, p. 1949 - 1956 (2017/05/29)
Tumor angiogenesis has become an important target for antitumor therapy, with most current therapies aimed at blocking the vascular endothelial growth factor (VEGF) pathway. The VEGF and its receptors have been implicated as key factors in tumor angiogenesis and are major targets in cancer therapy. A series of aryl-modified benzoylamino-N-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-heteroamides were synthesized from 2-amino-5,6-dimethoxy benzimidazole and aryl-substituted benzoylamino hetero acids. The new compounds were tested for inhibition of VEGF receptors I and II (VEGFR-1 and VEGFR-2). Compound 6e displayed VEGFR-2 inhibitory activity with a 50% inhibition concentration value as low as 0.020 μM in a homogeneous time-resolved fluorescence enzymatic assay. VEGFR-2 active compounds display good activity against VEGFR-1 as well.
FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS
-
Page/Page column 81, (2017/04/11)
An especially robust compound and its derivative metal complexes that are approximately one hundred-fold superior in catalytic performance to the previously invented TAML analogs is provided having the formula (I) wherein Y1, Y2, Y3 and Y4 are oxidation resistant groups which are the same or different and which form 5- or 6-membered rings with a metal, M, when bound to D; at least one Y incorporates a group that is significantly more stable towards nucleophilic attack than the organic amides of TAML activators; D is a metal complexing donor atom, preferably N; each X is a position for addition of a labile Lewis acidic substituent such as (i) H, deuterium, (ii) Li, Na, K, alkali metals, (iii) alkaline earth metals, transition metals, rare earth metals, which may be bound to one or more than one D, (iv) or is unoccupied with the resulting negative charge being balanced by a nonbonded counteraction; at least one Y may contain a site that is labile to acid dissociation, providing a mechanism for shortening complex lifetime. The new complexes deliver catalytic performances that promise to revolutionize multiple oxidation technology spaces including water purification.
Expanding the aqueous-based redox-facilitated self-polymerization chemistry of catecholamines to 5,6-dihydroxy-1H-benzimidazole and its 2-substituted derivatives
Fan, Ka Wai,Peterson, Matthew B.,Ellersdorfer, Peter,Granville, Anthony M.
, p. 25203 - 25214 (2016/03/22)
Aqueous-base redox-facilitated self-polymerization can be performed with 5,6-dihydroxy-1H-benzimidazole (DHBI) to generate polymeric material that is analogous to poly(dopamine) (PDA), proving the possibility to expand the catecholamine-exclusive chemistr
Development and in vivo quantitative magnetic resonance imaging of polymer micelles targeted to the melanocortin 1 receptor
Barkey, Natalie M.,Preihs, Christian,Cornnell, Heather H.,Martinez, Gary,Carie, Adam,Vagner, Josef,Xu, Liping,Lloyd, Mark C.,Lynch, Vincent M.,Hruby, Victor J.,Sessler, Jonathan L.,Sill, Kevin N.,Gillies, Robert J.,Morse, David L.
, p. 6330 - 6338 (2013/09/23)
Recent emphasis has focused on the development of rationally designed polymer-based micelle carriers for drug delivery. The current work tests the hypothesis that target specificity can be enhanced by micelles with cancer-specific ligands. In particular,
2,1,3-Benzoxadiazole and 2,1,3-benzothiadiazole-based fluorescent compounds: Synthesis, characterization and photophysical/electrochemical properties
Behramand, Behramand,Molin, Fernando,Gallardo, Hugo
, p. 600 - 605 (2012/11/06)
Six new fluorescent compounds derived from 2,1,3-benzoxadiazole and 2,1,3-benzothiadiazole heterocycles with varying numbers of alkoxy chains were successfully synthesized. Sonogashira cross-coupling was used as the key synthetic step to link the central and terminal aromatic units through an acetylenic linker unit which ensures molecular planarity and extension of the conjugation. All of the synthesized compounds showed UV-vis absorption in the 426-437 nm range with reasonably high molar extinction coefficients. All six compounds emit in the green region of the visible spectrum with reasonably large Stokes shifts (95-107 nm) and medium emission efficiencies (Φf = 0.27-0.32). Electrochemical studies showed that the compounds have closely spaced HOMO and LUMO energy levels and that they may present good electron transporting properties.
