339538-56-6

Basic information

• Product Name: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide
• Synonyms: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide
• CAS NO: 339538-56-6
• Molecular Weight: 384.358
• Mol File: 339538-56-6.mol

Chemical Properties

• CAS DataBase Reference: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide(339538-56-6)
• EPA Substance Registry System: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide(339538-56-6)

Safety Data

• Hazardous Substances Data: 339538-56-6(Hazardous Substances Data)

Upstream product

• 98276-57-4 2,4-Diamino-benzaldehyde 
• 109-89-7 diethylamine 
• 180340-74-3 4'-trifluoromethylbiphenyl-2-carbonyl chloride 

Downstream Products

• 339538-57-7 2-Methyl-7-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-quinoline-3-carboxylic acid ethyl ester 

Relevant articles and documents

7[4′-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and method of inhibiting the secretion of apolipoprotein B

This invention relates to compounds of Formula I that inhibit the secretion of apolipoprotein B, to pharmaceutical compositions comprising the compounds, and to methods of treating and/or preventing atherosclerosis, obesity, diabetes, hyperlipidemia, hyperliproproteinemia, hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia, pancreatitis, myocardial infarction, stroke, restenosis, or Syndrome X. This invention also relates to methods of reducing the secretion of apolipoprotein B and/or inhibiting microsomal triglyceride transfer protein.

Methods of making quinoline amides

The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines. The present invention also relates to compounds that are used to make quino