339541-03-6Relevant academic research and scientific papers
Ruthenium-catalyzed ring-opening and ring-closing enyne metathesis
Kitamura, Tsuyoshi,Mori, Miwako
, p. 1161 - 1163 (2001)
Matrix presented When a CH2Cl2 solution of an enyne containing the cycloalkene moiety was stirred in the presence of ruthenium-carbene complex (10 mol %) at room temperature under ethylene gas (1 atm), ring-opening and ring-closing m
ROM-RCM of cycloalkene-yne
Kitamura, Tsuyoshi,Kuzuba, Yuichi,Sato, Yoshihiro,Wakamatsu, Hideaki,Fujita, Reiko,Mori, Miwako
, p. 7375 - 7389 (2007/10/03)
Ring-opening metathesis and ring-closing metathesis (ROM-RCM) of cycloalkene-yne was demonstrated using a first- or second-generation ruthenium complex. When cycloalkenes bearing the alkyne part at the C-3 position were reacted with a first-generation ruthenium-carbene complex under an atmosphere of ethylene, ROM-RCM proceeded smoothly to give skeletal reorganized products in good yields. In this reaction, cycloalkene-ynes having terminal alkyne were suitable. On the other hand, when cycloalkenes bearing the alkyne part at the C-1 position were treated with a second-generation ruthenium-carbene complex, ROM-RCM proceeded smoothly to give bicyclic compounds and/or dimeric compounds in good yields.
