3397-30-6Relevant articles and documents
Synthesis of chiral TFA-protected α-amino aryl-ketone derivatives with friedel-crafts acylation of α-amino acid n-hydroxysuccinimide ester
Tachrim, Zetryana Puteri,Oida, Kazuhiro,Ikemoto, Haruka,Ohashi, Fumina,Kurokawa, Natsumi,Hayashi, Kento,Shikanai, Mami,Sakihama, Yasuko,Hashidoko, Yasuyuki,Hashimoto, Makoto
supporting information, (2017/11/07)
Chiral N-protected α-amino aryl-ketones are one of the useful precursors used in the synthesis of various biologically active compounds and can be constructed via Friedel-Crafts acylation of N-protected α-amino acids. One of the drawbacks of this reaction
Pattern-based recognition of heparin contaminants by an array of self-assembling fluorescent receptors
Jagt, Richard B. C.,Gomez-Biagi, Rodolfo F.,Nitz, Mark
supporting information; experimental part, p. 1995 - 1997 (2009/07/25)
(Figure Presented) Tracking down potential killers: Strong host-guest interactions enable the facile combination of polycationic cyclodextrin binding motifs (blue) with fluorescent reporters (orange) tethered to a hydrophobic guest molecule (dark green). An array of supramolecular fluorescent receptors prepared by this modular approach was used for the pattern-based recognition of negatively charged contaminants in the anticoagulant drug heparin.
REGULATORS OF THE HEDGEHOG PATHWAY, COMPOSITIONS AND USES RELATED THERETO
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Page/Page column 46, (2008/06/13)
The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgeh