33983-36-7

Upstream product

• 67-56-1 methanol 
• 19595-40-5 N²-(toluene-4-sulfonyl)-L-ornithine 
• 98-59-9 p-toluenesulfonyl chloride 
• 62631-17-8 Methyl N-δ-benzyloxycarbonyl-L-ornithinate 
• 110570-69-9 N⁵-benzyloxycarbonyl-N²-(toluene-4-sulfonyl)-L-ornithine methyl ester 
• 100616-51-1 N-(toluene-4-sulfonyl)-L-glutamic acid-1-methyl ester-5-nitrile 

Relevant academic research and scientific papers

Beta-amino acid derivatives as orally active non-peptide fibrinogen receptor antagonists

The ornithine sulfonamide 1 was identified by random screening as weak fibrinogen receptor antagonist. Homologation of the carboxylic acid function and further structure activity studies led to the development of novel beta-amino acid derivatives, which are potent and orally active antagonists of the platelet fibrinogen receptor GPIIb/IIIa.