33984-30-4

Usage

Uses

Used in Pharmaceutical Industry:
(4-CHLORO-PHENYLAMINO)-PHENYL-ACETIC ACID is used as a muscle relaxant for the treatment of muscle spasms and pain, providing relief by inhibiting nerve impulses in the brain and spinal cord. It is particularly beneficial for conditions such as muscle strains, sprains, and back pain, offering an effective therapeutic option for these common ailments.
Used in Pain Management:
As an anti-inflammatory agent, (4-CHLORO-PHENYLAMINO)-PHENYL-ACETIC ACID is used to manage pain associated with muscle injuries and inflammation. Its ability to reduce inflammation and relax muscles makes it a valuable component in pain management protocols for various musculoskeletal conditions.

InChI:InChI=1/C14H12ClNO2/c15-11-6-8-12(9-7-11)16-13(14(17)18)10-4-2-1-3-5-10/h1-9,13,16H,(H,17,18)

Upstream product

• 100-52-7 benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 1432610-78-0 C₁₈H₂₁ClN₂O 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 5634-59-3 Estere etilico dell'acido α-(4-clorofenilamino)-fenilacetico 

Downstream Products

• 57750-05-7 3-(4-chloro-phenyl)-4-phenyl-2,2-bis-trifluoromethyl-oxazolidin-5-one 
• 31419-17-7 N-[(1H-benzoimidazol-2-yl)-phenyl-methyl]-4-chloro-aniline 
• 57750-14-8 3-(4-chloro-phenyl)-7-diethylamino-6-methyl-4-phenyl-2,2-bis-trifluoromethyl-3,4-dihydro-2H-[1,3]oxazepin-5-one 
• 1233326-87-8 (4-chloro-phenylamino)-phenyl-acetic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester 

Relevant academic research and scientific papers

Cooperative copper-squaramide catalysis for the enantioselective N-H insertion reaction with sulfoxonium ylides

The first examples of a highly efficient and enantioselective carbene-mediated insertion reaction, from a sulfur ylide, are described. By way of a catalytic asymmetric insertion reaction into N-H bonds from carbonyl sulfoxonium ylides and anilines, using a copper-bifunctional squaramide cooperative catalysis approach, thirty-seven α-arylglycine esters were synthesized in enantiomeric ratios up to 92?:?8 (99?:?1 after a single recrystallization) and reaction yields ranging between 49-96%. Furthermore, the protocol benefits from quick reaction times and is conducted in a straightforward manner.

Boric acid catalyzed Ugi three-component reaction in aqueous media

B(OH)3 catalyzed Ugi three-component reaction for the synthesis of 2-arylamino-2-phenylacetamide has been developed using aldehydes, amines, and isocyanides in water. The synthesized 2-arylamino-2-phenylacetamides were efficiently converted int

N-SUBSTITUTED AMINO ACID DERIVATIVES WITH HYPERALPHALIPOPROTEINAEMIC ACTIVITY

A series of N-substituted amino acid derivatives was synthesized and the compounds were evaluated for their effects on serum total cholesterol, HDL cholesterol and triglycerides in experimental animals.Hyperalphalipoproteinaemic activity was found for some of these compounds tested, especially BRL 26314 (2) and related 3-aryl-2-aminopropionic acids.Structure-activity relationships are discussed.Keywords: N-substituted amino acid derivatives / hyperalphalipoproteinaemic activity