3401-57-8

Basic information

• Product Name: [(R)-2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[(benzylthio)methyl]ethyl]carbamic acid benzyl ester
• Synonyms: [(R)-2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[(benzylthio)methyl]ethyl]carbamic acid benzyl ester;CarbaMic acid, [2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[[(phenylMethyl)thio]Methyl]ethyl]-, phenylMethyl ester, (R)-
• CAS NO: 3401-57-8
• Molecular Formula: C₂₂H₂₂N₂O₆S
• Molecular Weight: 442.48
• Mol File: 3401-57-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [(R)-2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[(benzylthio)methyl]ethyl]carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(R)-2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[(benzylthio)methyl]ethyl]carbamic acid benzyl ester(3401-57-8)
• EPA Substance Registry System: [(R)-2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxo-1-[(benzylthio)methyl]ethyl]carbamic acid benzyl ester(3401-57-8)

Safety Data

• Hazardous Substances Data: 3401-57-8(Hazardous Substances Data)

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 3257-18-9 benzyloxycarbonyl-S-benzylcysteine 
• 107960-02-1 1,2,2,2-tetrachloroethyl-(N-succinimidyl)carbonate 

Downstream Products

• 75509-29-4 N-benzyloxycarbonyl-S-benzyl-L-cysteinylglycylglycine succinimido-ester 
• 75509-33-0 S-benyl-L-cysteinylglycylglycinamide 
• 75509-38-5 (R)-2-Amino-3-benzylsulfanyl-N-{[({(R)-2-benzylsulfanyl-1-[({[((R)-2-benzylsulfanyl-1-{[(carbamoylmethyl-carbamoyl)-methyl]-carbamoyl}-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-carbamoyl]-ethylcarbamoyl}-methyl)-carbamoyl]-methyl}-propionamide; hydrobromide 
• 75509-36-3 C₄₈H₆₂N₁₂O₁₂S₃ 
• 75509-37-4 N-benzyloxycarbonyl-S-benyzl-L-cysteinyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-cysteinylglycylglycinamide 
• 75509-35-2 (R)-2-Amino-3-benzylsulfanyl-N-({[((R)-2-benzylsulfanyl-1-{[(carbamoylmethyl-carbamoyl)-methyl]-carbamoyl}-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-propionamide; hydrobromide 
• 65710-06-7 (R)-2-[2-(2-Acetylamino-acetylamino)-acetylamino]-3-benzylsulfanyl-N-({[((R)-2-benzylsulfanyl-1-{[(carbamoylmethyl-carbamoyl)-methyl]-carbamoyl}-ethylcarbamoyl)-methyl]-carbamoyl}-methyl)-propionamide 
• 75509-34-1 N-benzyloxycarbonyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinylglycylglycinamid 
• 75509-32-9 N-acetyldiglycyl-S-benzyl-L-cysteinylglycylglycinamide 
• 75509-41-0 C₅₆H₇₁N₁₃O₁₂S₄*BrH 
• 75509-39-6 N-acetyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinylglycylglycinamide 
• 75509-40-9 N-benzyloxycarbonyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinyldiglycyl-S-benzyl-L-cysteinylglycylglycinamide 
• 77374-57-3 Z-Cys(Bzl)-Gly₃-Cys(Bzl)-Gly₃-Cys(Bzl)-Gly₂-NH₂ 
• 77374-51-7 Ac-Gly₂-Cys(Bzl)-Gly₂-Cys(Bzl)-Gly₃-Cys(Bzl)-Gly₂-NH₂ 

Relevant articles and documents

Novel Preparation of N-Protected Amino Acid Active Esters Using 1,2,2,2-Tetrachloroethyl Carbonates

1,2,2,2-Tetrachloroethyl chloroformate reacts with substituted phenols or N-hydroxy imides to yield crystalline and stable mixed aryl or oximido tetrachloroethyl carbonates.When allowed to react with an N-protected amino acid derivative, these compounds proved to be efficient for the syntheses of the corresponding active esters.A series of active esters including p-nitrophenol, trichlorophenol, pentafluorophenol, and N-hydroxysuccinimide derivatives were prepared by this new procedure.