34058-54-3Relevant academic research and scientific papers
Well-defined (NHC)Pd(N–heterocyclic carboxylate)(OAc) complexes-catalyzed direct C2-arylation of free (NH)-indoles with arylsulfonyl hydrazides
Yang, Jin,Zong, Ling-Li,Zhu, Xiao-Ting,Zhu, Xin-Ying,Zhao, Jian-Yi
, (2020/08/24)
A series of well-defined (NHC)Pd(N–heterocyclic carboxylate)(OAc) complexes (N–heterocyclic carboxylate = pyridine-2-carboxylate, quinoline-2-carboxylate and isoquinoline-1-carboxylate) were synthesized and fully characterized by NMR spectra, HR-MS and X-ray single crystal diffraction. The obtained complexes were then used for direct C2-arylation of free (NH)-indoles with arylsulfonyl hydrazides. With low catalyst loading, all complexes exhibited high catalytic activities for the arylation reactions.
A highly efficient and recyclable Fe3O4 magnetic nanoparticle immobilized palladium catalyst for the direct C-2 arylation of indoles with arylboronic acids
Zhang, Lei,Li, Pinhua,Liu, Can,Yang, Jin,Wang, Min,Wang, Lei
, p. 1979 - 1988 (2014/06/24)
A highly efficient Fe3O4 magnetic nanoparticle (MNP) immobilized palladium catalyst was prepared and applied to the direct C-2 arylation of indoles with arylboronic acids. The reactions generated the corresponding cross-coupling products in good yields. In addition, the supported catalyst with low loading (2.0 mol%) showed high stability and could be recovered and reused 8 times without significant loss of activity. The Royal Society of Chemistry 2014.
Microwave-accelerated Pd-catalyzed desulfitative direct C2-arylation of free (NH)-indoles with arylsulfinic acids
Miao, Tao,Li, Pinhua,Wang, Guan-Wu,Wang, Lei
, p. 3185 - 3190 (2014/01/06)
The rapid and efficient direct C2-arylation of free (NH)-indoles with arylsulfinic acids proceeded through a microwave-accelerated palladium-catalyzed desulfitation reaction. By using PdCl2 as a catalyst, silver acetate as an oxidant, and H2SO4 as an additive, arylsulfinic acids with both electron-donating and electron-withdrawing groups underwent desulfitative coupling with an array of free (NH)-indoles, thereby selectively providing C2-arylindoles in good yields. From C2 shining sea: The direct C2-arylation of free (NH)-indoles with arylsulfinic acids proceeded through a Pd-catalyzed desulfitation reaction. In the presence of an oxidant and an additive, 2-arylindoles were selectively afforded in good yields. Copyright
Synthesis of Pyranoazepines by Cycloaddition of Photochemically Generated 3-Alkoxycarbonyl-1,2-didehydroazepines with Enol Ethers
Tueckmantel, Werner
, p. 1165 - 1172 (2007/10/02)
3-Alkoxycarbonyl-1,2-didehydroazepines, generated by photolysis of alkyl 2-azidobenzoates, undergo a hetero-cycloaddition (stepwise or concerted) with ketone-derived enol ethers to form intensely colored, paratropic 6,8-dialkoxy-8,9-dihydropyrano4,3
Synthesis of Indole Derivatives from 2-Bromoanilines by a Palladium-assisted Reaction
Kasahara, Akira,Izumi, Taeko,Kikuchi, Tokio,Xiao-ping Lin
, p. 1555 - 1556 (2007/10/02)
In the presence of palladium(II) acetate, 2-bromoanilines readily react with enamines such as N-vinylpyrrolidone or α-piperidinostyrene to produce indole derivatives.
