106896-48-4

Basic information

• Product Name: 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER
• Synonyms: 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER;Methyl 3-aMino-2-broMobenzoate;Methyl 3-aMino-2-broMobenzoate 95%
• CAS NO: 106896-48-4
• Molecular Formula: C₈H₈BrNO₂
• Molecular Weight: 230.06
• Mol File: 106896-48-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 314.133 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: /
• Density: 1.583 g/mL at 25 °C
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: n20/D1.601
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER(106896-48-4)
• EPA Substance Registry System: 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER(106896-48-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• RIDADR: 2810
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 106896-48-4(Hazardous Substances Data)

Usage

Uses

Methyl 3-Amino-2-bromobenzoate is used in preparation of Carbazole-based compounds and its application as IDO inhibitor.

InChI:InChI=1/C8H8BrNO2/c1-12-8(11)5-3-2-4-6(10)7(5)9/h2-4H,10H2,1H3

Upstream product

• 67-56-1 methanol 
• 168899-61-4 3-amino-2-bromobenzoic acid 
• 4518-10-9 Methyl 3-aminobenzoate 
• 5337-09-7 2-bromo-3-nitro-benzoic acid methyl ester 
• 41085-43-2 2-bromo-3-nitrotoluene 
• 570-24-1 2-Methyl-6-nitroaniline 
• 53663-14-2 anhydro-2-hydroxymercuri-3-nitrobenzoic acid 
• 573-54-6 2-bromo-3-nitro-benzoic acid 

Downstream Products

• 610-94-6 2-bromobenzoic acid methyl ester 
• 246513-41-7 3-(3-Carbomethoxy-2-bromoanilino)-cyclohex-2-en-1-one 
• 1239349-10-0 methyl 2-bromo-3-formamidobenzoate 
• 1239349-12-2 methyl 2-bromo-3-(diethoxymethyleneamino)benzoate 
• 1403595-95-8 methyl 2-bromo-3-(cyclopentylamino)benzoate 
• 1403595-96-9 methyl 2-bromo-3-(cyclopentyl(methyl)amino)benzoate 
• 1403595-97-0 C₁₃H₁₆BrNO₂ 
• 1403597-87-4 methyl 3-(cyclopentyl(methyl)amino)-2-vinylbenzoate 
• 1403597-88-5 C₁₅H₁₉NO₂ 
• 112970-48-6 2-bromo-3-carbomethoxy-N-tosylaniline 
• 34058-54-3 methyl 2-phenyl-1H-indole-4-carboxylate 

Relevant articles and documents

Exploration of Biaryl Carboxylic Acids as Proton Shuttles for the Selective Functionalization of Indole C-H Bonds

A survey of diversely substituted 2-arylbenzoic acids were synthesized and tested for use as proton shuttle in the direct arylation of indoles with bromobenzenes. It was found that 3-ethoxy-2-phenylbenzoic acid gives superior yield and selectivity for this class of substrates.

SUBSTITUTED BENZENE COMPOUNDS

The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

Electrophilic bromination of meta-substituted anilines with N-bromosuccinimide: Regioselectivity and solvent effect

N-Bromosuccinimide-mediated electrophilic aromatic bromination of a series of anilines substituted with an electron-with-drawing group in the meta position was investigated. The regioselectivity of the reaction is markedly dependent on the polarity of the solvent and the bromination reaction can be tuned by appropriate selection of the reaction medium. Georg Thieme Verlag Stuttgart.