340732-72-1

Basic information

• Product Name: Benzenemethanol, 2-hydroxy-a-(4-methoxyphenyl)-
• Synonyms: 2-[Hydroxy-(4-methoxy-phenyl)-methyl]-phenol;benzhydryl alcohol;2-(hydroxy(4-methoxyphenyl)methyl)phenol
• CAS NO: 340732-72-1
• Molecular Formula: C14H14O3
• Molecular Weight: 230.263
• Mol File: 340732-72-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 392.2±21.0 °C(Predicted)
• Density: 1.214±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenemethanol, 2-hydroxy-a-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-hydroxy-a-(4-methoxyphenyl)-(340732-72-1)
• EPA Substance Registry System: Benzenemethanol, 2-hydroxy-a-(4-methoxyphenyl)-(340732-72-1)

Safety Data

• Hazardous Substances Data: 340732-72-1(Hazardous Substances Data)

Usage

Also known as

Hydroxyphenylpropionic acid

Upstream product

• 104-93-8 p-methylanizole 
• 90-02-8 salicylaldehyde 
• 117-99-7 2-Hydroxybenzophenone 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 1422447-30-0 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol 

Relevant articles and documents

Kinetics and mechanisms of hydration of o-Quinone methides in aqueous solution [10]

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Synthesis of 2 H-Chromenes via Unexpected [4 + 2] Annulation of Alkynyl Thioethers with o-Hydroxybenzyl Alcohols

A novel Br?nsted acid-catalyzed reaction of alkynyl thioethers with o-hydroxybenzyl alcohols via an unexpected formal [4 + 2] annulation has been developed. This metal-free protocol leads to the facile and practical synthesis of valuable polysubstituted 2

A base-promoted cascade reaction of α,β-unsaturated: N -tosylhydrazones with o -hydroxybenzyl alcohols: Highly regioselective synthesis of N-sec -alkylpyrazoles

An efficient method for the synthesis of N-sec-alkylpyrazoles through a base-promoted cascade cyclization/Michael addition reaction of α,β-unsaturated N-tosylhydrazones with ortho-hydroxybenzyl alcohols has been developed. The desired products containing di- or triaryl groups at the same carbon atom were afforded in good to excellent yields with excellent regioselectivities (>20:1). Moreover, a three-component reaction of ortho-hydroxybenzyl alcohols, α,β-unsaturated N-tosylhydrazones and saturated N-tosylhydrazones also took place to afford pyrazoles in good yields. This reaction offers a new route to triarylmethanes with a simple operation and is applicable for large-scale synthesis.

Visible-Light-Triggered C-C and C-N Bond Formation by C-S Bond Cleavage of Benzylic Thioethers

The cleavage of sulfidic C-S bonds under visible-light irradiation was harnessed to generate carbocations under neutral conditions and synthesize valuable di- and triarylalkanes as well as benzyl amines. To this end, photoredox catalysis and direct photoinduced C-S bond cleavage are used as complementary approaches and participate in the versatility of the general strategy. Extensive mechanistic studies have demonstrated the diversity of the reaction mechanism at work in these different reactions.