1422447-30-0

Basic information

• Product Name: 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol
• Synonyms: 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol
• CAS NO: 1422447-30-0
• Molecular Weight: 368.453
• Mol File: 1422447-30-0.mol

Chemical Properties

• CAS DataBase Reference: 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol(1422447-30-0)
• EPA Substance Registry System: 2-((4-methoxyphenyl)(p-tosyl)methyl)phenol(1422447-30-0)

Safety Data

• Hazardous Substances Data: 1422447-30-0(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 657-84-1 sodium tosylate 
• 340732-72-1 o-hydroxy-α-(p-anisyl)benzyl alcohol 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 90-02-8 salicylaldehyde 
• 824-79-3 sodium 4-methylbenzenesulfinate 

Downstream Products

• 1404300-85-1 2-benzyl-3-(4-methoxyphenyl)benzofuran 
• 61986-78-5 2-(1-(4-methoxyphenyl)-2,2-dimethylpropyl)phenol 
• 145275-53-2 2-<1-(4-methoxyphenyl)propyl>phenol 
• 796874-07-2 2-((4-methoxyphenyl)(phenanthren-9-yl)methyl)phenol 

Relevant articles and documents

Asymmetric Synthesis of 2,3-Dihydrobenzofurans by a [4+1] Annulation Between Ammonium Ylides and In Situ Generated o-Quinone Methides

A highly enantio- and diastereoselective [4+1] annulation between in situ generated ammonium ylides and o-quinone methides for the synthesis of a variety of 2,3-dihydrobenzofurans has been developed. The key factors controlling the reactivity and stereoselectivity were systematically investigated by experimental and computational means and the energy profiles obtained provide a deeper insight into the mechanistic details of this reaction.

Bifunctional Amine-Squaramide Catalyzed Friedel–Crafts Alkylation Based on ortho-Quinone Methides in Oil-Water Phases: Enantioselective Synthesis of Triarylmethanes

An efficient enantioselective Friedel–Crafts alkylation reaction of electron-rich β-naphthol with in situ generated ortho-quinone methides catalyzed by chiral bifunctional amine-squaramide catalysts has been developed. The chiral triarylmethane derivative

A Concise Synthesis of 2-(2-Hydroxyphenyl)acetonitriles via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols

A concise synthesis of 2-(2-hydroxyphenyl)acetonitriles has been developed through reaction of trimethylsilyl cyanide and the o-quinone methides in situ generated from 2-(1-tosylalkyl)phenols under basic conditions. In addition, 2-(2-hydroxyphenyl)acetonitriles could be conveniently transformed to benzofuranones.

A mild method for generation of o-quinone methides under basic conditions. the facile synthesis of trans-2,3-dihydrobenzofurans

A novel and efficient method for the generation of o-quinone methide intermediates was developed from the readily available 2-tosylalkylphenols under the mild basic conditions, and their reactions with sulfur ylides were investigated for the stereoselective synthesis of trans-2,3-dihydrobenzofurans. The Royal Society of Chemistry 2013.