34084-89-4

Usage

InChI:InChI=1/C10H7NO4S/c1-15-10(12)8-5-6-3-2-4-7(11(13)14)9(6)16-8/h2-5H,1H3

Upstream product

• 58755-57-0 2-chloro-3-nitrobenzaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 5274-70-4 3-nitrosalicylic aldehyde 
• 61063-03-4 3-nitro-2-(toluene-4-sulfonyloxy)-benzaldehyde 

Downstream Products

• 616238-78-9 7-amino-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 90407-22-0 7-nitrobenzothiophene-2-carboxylic acid 
• 17402-91-4 7-aminobenzothiophene 
• 105685-06-1 1-(benzo[b]thiophen-7-yl)piperazine 
• 616238-55-2 N-[2-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-6-(4-methoxy-benzylamino)-nicotinamide 
• 616238-60-9 N-[2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-6-chloronicotinamide 
• 616238-79-0 7-[(6-chloro-pyridine-3-carbonyl)-amino]-benzo[b]thiophene-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I' PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE "RIG-I" PATHWAY AND METHODS OF USE THEREOF

The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.

Preparation method of 7-piperazinyl benzothiophene or salt thereof

The invention discloses a preparation method of 7-piperazinyl benzothiophene or salt thereof, comprising the following steps: (1) carrying out substitution ring closing reaction on a compound 3 and acompound 4 to obtain a compound 5; (2) carrying out hydr

Method for preparing benzothiophene derivative

The invention relates to a method for preparing a benzothiophene derivative. The method comprises the following steps: taking 7-nitrothiophene as a raw material, and forming a thiophene derivative through nucleophilic substitution. The method provided by the invention has the advantages of mild reaction conditions, simple operation, controllable post-treatment and convenient quality control, and is beneficial to large-scale industrial production.

Discovery and optimization of p38 inhibitors via computer-assisted drug design

Integration of computational methods, X-ray crystallography, and structure-activity relationships will be disclosed, which lead to a new class of p38 inhibitors that bind to p38 MAP kinase in a Phe out conformation.

Compounds useful in treating cytokine mediated diseases

Disclosed are amide compounds of formula(I): wherein Ar1, Q, Y and R3-R6 of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating d