58755-57-0

Basic information

• Product Name: 2-CHLORO-3-NITROBENZALDEHYDE
• Synonyms: 2-CHLORO-3-NITROBENZALDEHYDE;Benzaldehyde, 2-chloro-3-nitro-;2-chloro-3-nitrobenzaldehyde58755-57-0
• CAS NO: 58755-57-0
• Molecular Formula: C₇H₄ClNO₃
• Molecular Weight: 185.56
• Mol File: 58755-57-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 293.493 °C at 760 mmHg
• Flash Point: 131.3 °C
• Appearance: /
• Density: 1.486 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CHLORO-3-NITROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-NITROBENZALDEHYDE(58755-57-0)
• EPA Substance Registry System: 2-CHLORO-3-NITROBENZALDEHYDE(58755-57-0)

Safety Data

• Hazardous Substances Data: 58755-57-0(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-Nitrobenzaldehyde is a synthetic, aromatic compound classified under the category of organochlorine compounds, specifically a monochlorobenzene comprised of a benzene core carrying a chloro and a nitro substituent at positions 2 and 3, respectively, as well as a formyl substituent at position 1. It is typically available in crystalline solid form with a molecular weight of 185.59 g/mol. As a reagent, 2-Chloro-3-Nitrobenzaldehyde is involved in the synthesis of a variety of chemical products and potentially has applications in biological studies or pharmaceuticals. Its unique chemical properties, including its reactivity, contribute to its usage in such complex chemical processes. However, like many chemicals, it should be handled with caution as it can cause harm to the eyes, skin, and respiratory tract upon exposure.

Upstream product

• 34915-64-5 C₈H₆ClNO₄ 
• 53663-14-2 anhydro-2-hydroxymercuri-3-nitrobenzoic acid 
• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 3970-40-9 2-chloro-3-nitrotoluene 
• 89639-98-5 (2-chloro-3-nitrophenyl)methanol 

Downstream Products

• 77150-16-4 3-Nitro-2-(4-oxo-4H-quinazolin-3-yl)-benzaldehyde 
• 112969-06-9 4-(2-chloro-3-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid dimethyl ester 
• 68064-95-9 2-[(2-chloro-3-nitrophenyl)methylene]-3-oxobutanoic acid, ethyl ester 
• 857040-81-4 2-(2-chloro-3-nitro-benzylamino)ethanol 
• 857040-99-4 (2S,2S)-2-(2-chloro-3-nitrobenzylamino)-3-methylpentan-1-ol 
• 96516-29-9 2-fluoro-3-nitrobenzaldehyde 
• 77150-19-7 2-(8-Iodo-4-oxo-4H-quinazolin-3-yl)-3-nitro-benzaldehyde 
• 77150-17-5 2-(8-Bromo-4-oxo-4H-quinazolin-3-yl)-3-nitro-benzaldehyde 
• 22233-62-1 3,3'-Dinitro-2,2'-dichlor-desoxybenzoin 
• 34084-89-4 7-nitro-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 89795-79-9 benzo[d]isothiazol-7-amine 
• 89641-97-4 7-nitro-1,2-benzisothiazole 
• 105685-06-1 1-(benzo[b]thiophen-7-yl)piperazine 
• 17402-91-4 7-aminobenzothiophene 

Relevant articles and documents

Visible-light assisted of nano Ni/g-C3N4 with efficient photocatalytic activity and stability for selective aerobic C?H activation and epoxidation

A selective, economical, and ecological protocol has been described for the oxidation of methyl arenes and their analogs to the corresponding carbonyl compounds and epoxidation reactions of alkenes with molecular oxygen (O2) or air as a green oxygen source, under mild reaction conditions. The nano Ni/g-C3N4 exhibited high photocatalytic activity, stability, and selectivity in the C?H activation of methyl arenes, methylene arenes, and epoxidation of various alkenes under visible- light irradiation without the use of an oxidizing agent and under base free conditions.

Iterative design of a biomimetic catalyst for amino acid thioester condensation

Herein, the design of a catalyst that combines lessons learned from peptide biosynthesis, enzymes, and organocatalysts is described. The catalyst features a urea scaffold for carbonyl recognition and elements of nucleophilic catalysis. In the presence of 10 mol % of the organocatalyst, the rate of peptide bond formation is accelerated by 10000-fold over the uncatalyzed reaction between Fmoc-amino acid thioesters and amino acid methyl esters.

Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic - Targeting Mycobacterium tuberculosis ribonucleotide reductase

Peptides mimicking the C-terminus of the small subunit (R2) of Mycobacterium tuberculosis ribonucleotide reductase (RNR) can compete for binding to the large subunit (R1) and thus inhibit RNR activity. Moreover, it has been suggested that the binding of t