34102-49-3

Usage

Chemical Properties

white to off-white powder or chunks

InChI:InChI=1/C7H11NO/c9-7-5-3-1-2-4-6(5)8-7/h5-6H,1-4H2,(H,8,9)/t5-,6-/m1/s1

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 110-82-7 cyclohexane 
• 110-83-8 cyclohexene 
• 34914-36-8 2-(triphenylmethylthio)ethanoic acid 
• 538-75-0 dicyclohexyl-carbodiimide 

Downstream Products

• 5691-20-3 (1RS,2SR)-2-aminocyclohexanecarboxylic acid 
• 129169-56-8 (1S,6R)-8-Oxo-7-aza-bicyclo[4.2.0]octane-7-carboxylic acid (3-chloro-phenyl)-amide 
• 24716-92-5 (±)-cis-2-aminocyclohexane-1-carboxylic acid hydrochloride 
• 129169-57-9 (1S,6R)-8-Oxo-7-aza-bicyclo[4.2.0]octane-7-carboxylic acid (4-chloro-phenyl)-amide 
• 128694-24-6 (3bS,7aR)-7b-Ethylsulfanyl-3-(2-nitro-phenyl)-4,5,6,7,7a,7b-hexahydro-3bH-1-oxa-2,3a-diaza-cyclopenta[3,4]cyclobuta[1,2]benzene 
• 128694-22-4 (3bS,7aR)-7b-Ethylsulfanyl-3-(4-methoxy-phenyl)-4,5,6,7,7a,7b-hexahydro-3bH-1-oxa-2,3a-diaza-cyclopenta[3,4]cyclobuta[1,2]benzene 
• 128694-23-5 (3bS,7aR)-7b-Ethylsulfanyl-3-phenyl-4,5,6,7,7a,7b-hexahydro-3bH-1-oxa-2,3a-diaza-cyclopenta[3,4]cyclobuta[1,2]benzene 
• 1043-46-5 1,3,5-triphenyl-1,2,4-triazole 
• 109087-15-2 cis-2-hydroxymethylcyclohexylamine 
• 40015-88-1 (1R,2S)-methyl 2-aminocyclohexanecarboxylate 

Relevant academic research and scientific papers

Nylon-3 polymers that enable selective culture of endothelial cells

Substrates that selectively encourage the growth of specific cell types are valuable for the engineering of complex tissues. Some cell-selective peptides have been identified from extracellular matrix proteins; these peptides have proven useful for biomat

Hairpin folding behavior of mixed α/β-peptides in aqueous solution

The invention of new strategies for the design of protein-mimetic oligomers that manifest the folding encoded in natural amino acid sequences is a significant challenge. In contrast to the α-helix, mimicry of protein β-sheets is less understood. We report

Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening

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Access to poly-β-peptides with functionalized side chains and end groups via controlled ring-opening polymerization of β-lactams

Poly-β-peptides are attractive for biomedical applications because the backbone is similar enough to that of proteins for biocompatibility,but the backbone is sufficiently unnatural that these polymers evade pr oteolytic degradation. Prior investigations

Synthesis of 1-[2-(hydroxymethyl)cyclohexyl]pyrimidine analogues of nucleosides: A comparative study

The synthesis of a new series of 1,2-disubstituted carbonucleosides analogues of pyrimidine (cyclohexane derivatives) is reported. For the synthesis of the uridine analogue 5a, either construction of the base on the amino group of the amino alcohol 3 or o

Large-scale syntheses of FMOC-protected non-proteogenic amino acids: Useful building blocks for combinatorial libraries

Convenient and reliable large-scale procedures for the protection of various amino acids with N-(9-fluorenylmethoxycarbonyl)oxysuccinimide (FMOC-OSu) are described. Commercially available 4-aminomethylbenzoic acid and trans-4-(aminomethyl)cyclohexanecarbo

1,2-Disubstituted cyclohexane carbocyclic analogues of nucleosides

Several compounds of a new series of cyclohexane-based 1,2-disubstituted carbonucleoside analogues, were synthesized. The adenine and uridine derivatives, were prepared by construction of the heterocyclic base on the primary amino group of 2-aminocyclohexylmethanol, and the thymine derivative by condensation of 2-hydroxycyclohexylmethanol with thymine using the Mitsunobu reaction.

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1

Based on X-ray crystal structure information, mono charged phosphinate isosteres of phosphotyrosine have been designed and incorporated in a short inhibitory peptide sequence of the Grb2-SH2 domain. The resulting compounds, by exploiting additional interactions, inhibit binding to the Grb2-SH2 domain as potently as the corresponding doubly charged (phosphonomethyl)phenylalanine analogue. (C) 2000 Elsevier Science Ltd.

5-HT3 receptor agonist, novel thiazole derivative and intermediate thereof

A 5-HT3 receptor against containing a thiazole derivative as the effective ingredient is provided and is represented by the Formula (I): STR1 wherein the A ring is substituted or unsubstituted and represents a benzene or a heterocyclic ring with one or two heteroatoms; one of L1 or L2 represents a single bond and the other is non-existent or represents an alkylene or alkenylene group; R represents: STR2

STEREOCHEMICAL STUDIES, 144. SATURATED HETEROCYCLES, 151. PREPARATION OF cis AND trans-CYCLOALKANE-CONDENSED PYRIMIDINEDIONES BY AZETIDINONE RING TRANSFORMATION

N-substituted derivatives (3 and 4) obtained from cyclopentane- and cyclohexane-azetidinones (1 and 2) were isomerized with polyphosphoric acid to give cyclopentane-cis- (6) and cyclohexane-trans-condensed (7) 2,4-pyrimidinediones.The structures of the dihydrouracils prepared by the ring transformation were proved by 1H- and 13C-nmr spectroscopy and by comparison with the compounds synthesized from cis- and trans-2-amino-1-cycloalkanecarboxamides (11-13) with 1,1'-carbonyldiimidazole.