34130-51-3

Usage

Uses

Used in Food Industry:
Methyl 2-(3-oxocyclopentyl)acetate is used as a flavoring agent to impart a fruity, pineapple-like aroma to various food products, enhancing their overall taste and appeal.
Used in Cosmetic Industry:
In the cosmetic industry, Methyl 2-(3-oxocyclopentyl)acetate serves as a fragrance ingredient, adding a sweet, fruity scent to products such as perfumes, lotions, and other personal care items.
Synthesis:
Methyl 2-(3-oxocyclopentyl)acetate is synthesized through the esterification of 3-oxocyclopentylacetic acid with methanol, making it a chemically derived compound.
Safety:
It is considered safe for use in food and consumer products, ensuring that the products containing Methyl 2-(3-oxocyclopentyl)acetate do not pose any health risks to consumers.

Upstream product

• 67-56-1 methanol 
• 68931-50-0 (3-Oxo-cyclopentyl)-thioacetic acid S-tert-butyl ester 
• 930-30-3 cyclopent-2-enone 
• 598-25-4 Dimethylallene 
• 36850-80-3 [(1-methoxyvinyl)oxy]trimethylsilane 
• 1019842-24-0 3-(3-oxo-cyclobutyl)-propionic acid methyl ester 
• 1019842-07-9 3-(2,2-dichloro-3-oxo-cyclobutyl)-propionic acid methyl ester 
• 818-57-5 Methyl 4-pentenoate 
• 111209-96-2 3-(1,1-Bismethoxycarbonylmethyl)cyclopent-1-one 
• 25432-03-5 hex-3-enedioic acid diethyl ester 
• 4436-74-2 hex-3-ene-1,6-dicarboxylic acid 
• 3588-17-8 (2E,4E)-2,4-hexadienedioic acid 
• 1004-20-2 1-oxabicyclo<3.2.1>octan-2-one 
• 186581-53-3 diazomethane 

Downstream Products

• 29119-47-9 (2R*,3S*)-3-methoxycarbonylmethyl-2-(2-pentynyl)cyclopentanone 
• 2570-03-8 (+/-)-methyl trans-dihydrojasmonate 
• 1211-29-6 methyl jasmonate 

Relevant academic research and scientific papers

Controllable Skeleton Rearrangement of 3-Substituted Cyclobutanones under Basic Conditions?

Divergent skeleton rearrangements of cyclobutanones under simply basic conditions have been described. The reaction pathway is controlled by the nature of Z group on 3-substituted cyclobutanones, leading to the formation of various lactones, lactams and a

HIV Integrase Inhibitors

The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

An environmentally friendly procedure for Mukaiyama aldol and Mukaiyama-Michael reactions using a catalytic amount of DBU under solvent- and metal-free conditions

Mukaiyama aldol and Mukaiyama-Michael reactions can proceed smoothly in the presence of a catalytic amount of DBU (20% mmol), to afford the corresponding products in moderate to good yields. This solvent- and metal-free approach provides an environmentall

Behaviour of unsaturated methyl esters with cyclopentaneacetic acid skeleton in the presence of mild lewis acids. Alkylation versus addition and lactonization

The reactions of methyl 2-and 3-cyclopentenylacetate, 2-Me and 3-Me, in the presence of AlCl3/CH3NO2 or FeCl3 in benzene or in nitromethane were studied. The major products obtained in benzene were the kinetically controlled benzene alkylation compounds (6-Me as major and trans-and cis-5-Me as minor phenylated products) and the unexpected lactone 7 and hydroxyester 8. In order to understand the pathway in which the last products are formed, we made the unsaturated esters react in the absence of the aromatic substrate, in nitromethane. There are three types of products: double bond isomerization products (1-, 2-and 3-Me), H2O and HCl addition products (8 and 9) and lactone 7. The proton traces in the reaction medium cannot explain the good yields of the two last types of products. Therefore, it seems possible that the reaction may occur in two steps, (a) in the mixture of esters and catalyst and (b) during the decomposition in aqueous HCl solution. In step (a), an advanced charge polarization takes place under the influence of the Lewis acidity of the catalyst and also of the favourable steric assistance of the oxygen nonbonding pair of electrons in carbomethoxy group. In step (b), the formed complexes react with H2O and HCl to produce the addition compounds and the lactone. The key intermediate in the formation of 8 is probable an organometallic compound, I, (represented for the ester 2-Me in Scheme 1). Its precursor is a transition state, TS1, which is formed as a result of the redistribution of the oxygen nonbonding electrons and of the πC=C electrons at the same time with the implication of the metal catalyst's vacant orbital.

CONJUGATE ADDITIONS OF THE CROWN-POTASSIUM ENOLATE COMPLEXES

Achiral and chiral crowns complexed with potassium bases catalyze the Michael additions of enolates to cycloalkenones.

REGIOCONTROL BY ELECTRON WITHDRAWING GROUPS IN THE Rh-CATALYZED C-H INSERTION OF α-DIAZOKETONES

It is possible to control the regiochemistry of the Rh-catalyzed insertion of α-diazoketones into C-H bonds by taking advantage of the greatly reduced rate of insertion into methylenes which are α or β to a carbonyl function.The 2-carboxyethyl group is especially useful for this purpose because it can be transformed eventually into a variety of other substituents.

Regioselective Photocycloaddition of 2-Cyclopentenone to Some Allenes

Irradiation (λ>295 nm) of 2-cyclopentenone in the presence of 3-methyl-1,2-butadiene, 2-methyl-2,3-pentadiene, and 1,2-cyclononadiene gave mixtures of cycloadducts in good yields (>78percent).The mixtures contained head-to-head and head-to-tail isomers in an approximate ratio of 80:20.The additions to the acyclic allenes occurred across the less highly substituted double bond.The mechanism of the reactions is discussed.

JUVENILE HORMONE ANALOGS. PART XVII. SYNTHESIS OF ETHYL AND ISO-PROPYL 4--3-METHYL-2-BUTENOATES.

Syntheses of the title compounds, prepared for investigation of their activity as insect growth regulators are described.