341553-94-4Relevant academic research and scientific papers
Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2′,3′-didehydro-2′,3′-dideoxy-2′- fluorocarbocyclic nucleosides
Wang, Jianing,Jin, Yunho,Rapp, Kimberly L.,Bennett, Matthew,Schinazi, Raymond F.,Chu, Chung K.
, p. 3736 - 3748 (2007/10/03)
Carbocyclic nucleosides have received much attention due to their interesting biological activity and metabolic stability. Among nucleoside analogues, a fluorine substitution on the carbohydrate moiety or introduction of a 2′,3′-unsaturated structure moti
Solid Phase Synthesis of Carbocyclic L-2′-Deoxynucleosides
Choo, Hyunah,Chong, Youhoon,Chu, Chung K.
, p. 1471 - 1473 (2007/10/03)
matrix presented Carbocyclic L-2'deoxynucleosides 17 were synthesized on solid phase in four steps from the appropriately protected intermedate 11. The Mitsunobu reaction was used as a condensation method between the carbocyclic moiety and heterocyclic ba
