3416-74-8 Usage
Uses
Used in Organic Synthesis:
1-Chloro-4-nonyne is used as a versatile building block for the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and reactivity make it a valuable starting material in the development of new compounds with potential applications in various industries.
Used in Pharmaceutical Industry:
1-Chloro-4-nonyne is used as a key intermediate in the synthesis of pharmaceuticals for the treatment of various diseases and conditions. Its reactivity allows for the formation of new chemical entities with potential therapeutic properties, contributing to the advancement of drug discovery and development.
Used in Agrochemical Industry:
1-Chloro-4-nonyne is employed as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides. Its ability to participate in various chemical reactions enables the creation of new compounds with improved efficacy and selectivity, enhancing crop protection and agricultural productivity.
Used in Fine Chemicals Industry:
1-Chloro-4-nonyne is utilized as a precursor in the production of fine chemicals, which are high-purity chemicals used in various applications, including fragrances, dyes, and specialty materials. Its versatility in organic synthesis allows for the development of novel fine chemicals with unique properties and applications.
Safety Considerations:
It is important to handle 1-Chloro-4-nonyne with care, as it can be hazardous to health and the environment. Proper safety measures, such as wearing protective equipment and working in a well-ventilated area, should be taken when working with 1-Chloro-4-nonyne to minimize potential risks.
Check Digit Verification of cas no
The CAS Registry Mumber 3416-74-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,1 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3416-74:
(6*3)+(5*4)+(4*1)+(3*6)+(2*7)+(1*4)=78
78 % 10 = 8
So 3416-74-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H15Cl/c1-2-3-4-5-6-7-8-9-10/h2-4,7-9H2,1H3
3416-74-8Relevant academic research and scientific papers
Alkylation of Terminal Alkynes under Zinc Lewis Acid Catalysis and Its Mechanistic Studies
Osano, Mana,Kida, Takeru,Yonekura, Kyohei,Tsuchimoto, Teruhisa
supporting information, p. 2825 - 2831 (2019/04/13)
With a zinc Lewis acid catalyst and proton sponge in toluene, terminal alkynes were found to undergo the alkylation by alkyl triflates to provide unsymmetrical internal alkynes. This is the first example that a simple alkyl chain other than benzylic and norbornyl units can be introduced onto the alkynyl carbon atom under Lewis acid catalysis. Mechanistic studies revealed that the activation of the alkyne by the zinc Lewis acid and proton sponge is the trigger of the reaction to give a monoalkynylzinc species, which successively reacts with the alkyl triflate to afford the internal alkyne. A radical pathway is unlikely in this system. (Figure presented.).
Kolbe Synthesis of Unsaturated Pheromones by Coelectrolysis with 5-Alkynoic Acids
Seidel, Wolfgang,Schaefer, Hans J.
, p. 3898 - 3903 (2007/10/02)
The alkynoic acids 5a - g are synthesized by coelectrolysis of 5-alkynoic acids 2a - c with dicarboxylic monoesters 3a - d.By reduction, Lindlar-hydrogenation, and acetylation these are converted into pheromones such as (Z)-11-hexadecenyl acetate (7b), the pheromone of Mamestra brassicae. 2a - c can be prepared by alkynylation of 1-bromo-3-chloropropane to 1a - c, substitution by cyanide and hydrolysis.
