34173-49-4

Basic information

• Product Name: N-cyclohexyl-N-methylbenzo[d]oxazol-2-amine
• Synonyms: N-cyclohexyl-N-methylbenzo[d]oxazol-2-amine
• CAS NO: 34173-49-4
• Molecular Weight: 230.31
• Mol File: 34173-49-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-N-methylbenzo[d]oxazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-N-methylbenzo[d]oxazol-2-amine(34173-49-4)
• EPA Substance Registry System: N-cyclohexyl-N-methylbenzo[d]oxazol-2-amine(34173-49-4)

Safety Data

• Hazardous Substances Data: 34173-49-4(Hazardous Substances Data)

Upstream product

• 615-18-9 2-chloro-1,3-benzoxazole 
• 98-94-2 N,N-dimethyl-cyclohexanamine 
• 100-60-7 N-methylcyclohexylamine 
• 273-53-0 benzoxazole 

Relevant articles and documents

Synthesis of 2-Deoxy-C-Glycosides via Iridium-Catalyzed sp2 and sp3 C—H Glycosylation with Unfunctionalized Glycals?

A new protocol for the synthesis of 2-deoxy-C-aryl-glycosides and 2-deoxy-C-alkyl-glycosides via iridium-catalyzed directed C—H glycosylation with glycals is reported. The method is amenable for both the C2 C—H glycosylation of indoles and the methyl C—H glycosylation of secondary methyl amines under the control of an N-linked benzoxazole directing group. The benzoxazole group can be cleanly removed by the treatment of KOH or LiAlH4.

N-Bromosuccinimide as an oxidant for the transition-metal-free synthesis of 2-aminobenzoxazoles from benzoxazoles and secondary amines

A facile and transition-metal-free method was developed through merging the ring opening of benzoxazoles with secondary amines and N-bromosuccinimide (NBS) mediated oxidative cyclization toward the synthesis of 2-aminobenzoxazoles. NBS was selected as a powerful oxidant in the oxidative cyclization of ring-opening amidines to provide the desirable 2-aminobenzoxazoles in excellent yields (up to 94%).