3420-63-1

Usage

Type of compound

Organic compound

Derivative of

Urea

Contains

Phenyl group and 3-chloropropyl group

Application

Herbicide

Mechanism of action

Inhibits plant growth by interfering with protein synthesis

Usage

Control of weeds in agricultural settings

Classification

Selective herbicide

Physical state

Crystalline solid

Solubility

Sparingly soluble in water

Application methods

Spray or granule in agricultural fields

Upstream product

• 13010-19-0 3-Chloropropyl isocyanate 
• 62-53-3 aniline 
• 4635-59-0 4-Chlorobutanoyl chloride 

Downstream Products

• 13907-69-2 C₁₀H₁₂ClN₃O₂ 
• 2933-50-8 ([1,3]oxazinan-2-ylidene)-(phenyl)-amine 
• 56535-85-4 3,4,5,6-tetrahydro-1-phenylpyrimidin-2(1H)-one 
• 1311946-34-5 4-fluorophenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-32-3 4-chlorophenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-30-1 4-tolyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-29-8 3,4,5-trimethoxyphenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-28-7 3-fluorophenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-27-6 3-methoxyphenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-26-5 3-tolyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-24-3 2,4,6-trichlorophenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-22-1 2,4,5-trichlorophenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-20-9 2,4-dimethylphenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 
• 1311946-19-6 2-propylphenyl 4-[tetrahydro-2-oxopyrimidin-1(2H)-yl]benzenesulfonate 

Relevant academic research and scientific papers

Design, synthesis, biological evaluation, and Structure - Activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4

Sixty-one phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates (PIB-SOs) and 13 of their tetrahydro-2-oxopyrimidin-1(2H)-yl analogues (PPB-SOs) were prepared and biologically evaluated. The antiproliferative activities of PIB-SOs on 16 cancer cell lines are

SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS

Compounds of formula (I): wherein R1, R2, R3, R4, R7, R6, R7, R8, R9, A, X and Y as defined herein are provided as useful for the treatment of cancer or for

Cyclic ureas as ortho directing substituents

Six-membered cyclic ureas are shown to have a weak ortho directing ability when linked through nitrogen to benzene and pyridine rings.

New substituted 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with α2-adrenoceptor antagonist activity

The emergence of a novel theory concerning the role of noradrenaline in the progression and the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases has provided a new impetus toward the discovery of novel compounds acting at α2-adrenoceptors. A series of substituted 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl derivatives bearing an amide, urea, or imidazolidinone moiety was studied. Some members of this series of compounds proved to be potent α2-adrenoceptor antagonists with good selectivity versus α1-adrenergic and D2-dopamine receptors. Particular emphasis is given to compound 33g which displays potent α2-adrenoceptor binding affinity in vitro and central effects in vivo following oral administration.