342023-84-1

Basic information

• Product Name: 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester
• Synonyms: 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester
• CAS NO: 342023-84-1
• Molecular Weight: 306.364
• Mol File: 342023-84-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester(342023-84-1)
• EPA Substance Registry System: 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester(342023-84-1)

Safety Data

• Hazardous Substances Data: 342023-84-1(Hazardous Substances Data)

Usage

Synthetic compound

A human-made chemical substance This term indicates that the compound is not naturally occurring and is created through chemical synthesis.

Pyrazole class

A group of organic compounds This term refers to the classification of the compound within the larger category of organic compounds, specifically those containing a pyrazole ring.

Building block

Used in the synthesis of pharmaceuticals and agrochemicals This property highlights the compound's role as a fundamental component in creating other, more complex molecules for use in drugs and agricultural chemicals.

Potential biological activities

Possesses possible therapeutic effects This indicates that the compound may have beneficial effects on biological systems and could be further researched for potential medical applications.

Starting material

Used in the development of new drugs This property emphasizes the compound's potential as a base for creating novel pharmaceuticals, contributing to drug discovery efforts.

Treatment potential

Studied for various medical conditions This suggests that researchers have explored or are exploring the compound's possible use in treating different health issues, though it may not yet be clinically established.

Versatile chemical

Wide range of applications in drug discovery and chemical research This term describes the compound's adaptability and usefulness in multiple areas of scientific study, particularly in the development of new drugs and the investigation of chemical properties and reactions.

Upstream product

• 1073-62-7 N-benzylhydrazine hydrochloride 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 20570-96-1 benzylhydrazine dihydrochloride 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 66129-60-0 ethyl-3-(dimethylamino)-2-(phenylcarbonyl)prop-2-enoate 

Downstream Products

• 905590-04-7 1-benzyl-5-phenyl-1H-pyrazole-4-carboxylic acid 
• 342023-85-2 (1-benzyl-5-phenyl-1H-pyrazol-4-yl)methanol 

Relevant articles and documents

CYCLIC AMINE COMPOUND AND USE THEREOF

The present invention relates to a compound represented by the formula:( I ) wherein ring A is a 5- or 6-membered aromatic heterocycle optionally having substituent (s); U, V and W are each independently C or N, provided that when any one of U, V and W is N, then the others should be C; Ra and Rb are each independently a cyclic group optionally having substituent (s), a C1-10 alkyl group optionally having substituent (s), a C2-10 alkenyl group optionally having substituent (s), or a C2-10alkynyl group optionally having substituent (s); X is a bond, or a spacer having 1 to 6 atoms in the main chain; Y is a spacer having 1 to 6 atoms in the main chain; Rc is a hydrocarbon group optionally containing heteroatom(s) as the constituting atom(s), which optionally has substituent (s); m and n are each independently 1 or 2; and ring B optionally further has substituent (s), or a salt thereof. The compound of the present invention has excellent renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension, and the like.

5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

Use of a compound of the formula: wherein R represents a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; X represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -CO-, -CS-, -CR(OR)- or -NR- wherein each of R and R represents a hydrogen atom or a hydrocarbon group which may be substituted, R represents a hydrogen atom or a protective group for a hydroxyl group; m represents an integer of 0 to 3; Y represents an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -NR-, -CONR- or -NRCO- wherein R represents a hydrogen atom or a hydrocarbon group which may be substituted; ring A represents an aromatic ring which may further have 1 to 3 substituents; n represents an integer of 1 to 8; ring B represents a nitrogen-containing 5-membered hetero ring which may further be substituted by an alkyl group; X represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO2-, -O-SO2- or -NR- wherein R represents a hydrogen atom or a hydrocarbon group which may be substituted; R represents a hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; W represents a bond or a divalent hydrocarbon residue having 1 to 20 carbon atoms; R represents a group of the formula: -OR (R represents a hydrogen atom or a hydrocarbon group which may be substituted) or -NRR (each of R and R, whether identical or not, represents a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, or an acyl group which may be substituted; R and R may bind together to form a ring); or a salt thereof, for the manufacture of a pharmaceutical preparation for preventing or treating syndrome X.