34223-82-0

Basic information

• Product Name: 3,6-dichloro-9H-fluoren-9-one
• Synonyms: 9H-Fluoren-9-one, 3,6-dichloro-; Fluoren-9-one, 3,6-dichloro-
• CAS NO: 34223-82-0
• Molecular Formula: C₁₃H₆Cl₂O
• Molecular Weight: 249.0921
• Mol File: 34223-82-0.mol

Chemical Properties

• Boiling Point: 416.7°C at 760 mmHg
• Flash Point: 176°C
• Density: 1.476g/cm³
• Vapor Pressure: 3.75E-07mmHg at 25°C
• Refractive Index: 1.679
• CAS DataBase Reference: 3,6-dichloro-9H-fluoren-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-dichloro-9H-fluoren-9-one(34223-82-0)
• EPA Substance Registry System: 3,6-dichloro-9H-fluoren-9-one(34223-82-0)

Safety Data

• Hazardous Substances Data: 34223-82-0(Hazardous Substances Data)

Upstream product

• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 84459-33-6 2-bromo-4-chlorobenzaldehyde 
• 92426-51-2 N-2-(6-Chlor-9-oxo-fluorenyl)-acetamid 
• 7145-81-5 N-2-(3.6-Dichlor-9-oxo-fluorenyl)-acetamid 
• 132384-36-2 2,7-bis-acetylamino-3,6-dinitro-fluoren-9-one 
• 5459-48-3 3,6-dinitro-2,7-diacetamidofluorene 
• 132384-37-3 2,7-diamino-3,6-dinitro-fluoren-9-one 
• 304-28-9 N,N'-(9H-fluorene-2,7-diyl)diacetamide 
• 58160-31-9 3,6-dinitrofluoren-9-one 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 20872-11-1 5,5’-dichlorobiphenyl-2,2’-dicarboxylic acid 
• 541540-05-0 3,6-dichloro-9-carbethoxyfluorene 
• 510-15-6 chlorobenzilate 
• 34966-48-8 ethyl 2-(4-chlorophenyl)-2-oxoacetate 

Relevant articles and documents

MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF

The disclosure relates to compounds and pharmaceutical compositions capable of modulating the hydroxysteroid 17-beta dehydrogenase (HSD17B) family member proteins including inhibiting the HSD17B member proteins, e.g. HSD17B13. The disclosure further relates to methods of treating liver diseases, disorders, or conditions with the compounds and pharmaceutical compositions disclosed herein, in which the HSD17B family member protein plays a role.

Dications of fluorenylidenes. The effect of substituent electronegativity and position on the antiaromaticity of substituted tetrabenzo[5.5]fulvalene dications

Oxidation of 3,6-disubstituted tetrabenzo[5.5]fulvalenes by SbF5 results in the formation of dications that behave like two antiaromatic fluorenyl cations connected by a single bond. Both fluorenyl systems exhibit the paratropic shifts and nucleus independent chemical shifts (NICS) characteristic of antiaromatic species. Comparison with analogous 2,7-disubstituted tetrabenzo[5.5]fulvalenes reveals that the antiaromaticity of the substituted ring system can be altered substantially by changes in the placement of the substituents, possibly due to changes in the delocalization of charge in the system. Substituents in the 3,6-position decrease the antiaromaticity because of the increase in the benzylic resonance compared to 2,7-substituents.