510-15-6

Usage

Uses

Used in Pharmaceutical Synthesis:
4,4'-Dichlorobenzilic acid ethyl ester is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of diverse chemical entities, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 4,4'-Dichlorobenzilic acid ethyl ester serves as a versatile building block in the production of a range of agrochemicals. Its ability to form a variety of chemical structures makes it valuable for the development of new pesticides and other agricultural chemicals.
Used in Organic Compound Synthesis:
4,4'-Dichlorobenzilic acid ethyl ester is utilized as a reagent in the laboratory for the formation of new organic compounds. Its high reactivity and potential for creating diverse chemical structures make it an essential component in organic chemistry research and development.
Used in Chemical Product Manufacturing:
This chemical compound is also used as a building block in the production of various chemical products. Its versatility and reactivity contribute to the creation of a wide array of chemical entities for different applications across various industries.

InChI:InChI=1/C16H14Cl2O3/c1-2-21-15(19)16(20,11-3-7-13(17)8-4-11)12-5-9-14(18)10-6-12/h3-10,20H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 23851-46-9 bis(4-chlorophenyl)(hydroxy)acetic acid 
• 115-32-2 Dicofol 
• 106-39-8 bromochlorobenzene 
• 34966-48-8 ethyl 2-(4-chlorophenyl)-2-oxoacetate 
• 3457-46-3 4,4'-dichlorobenzil 

Downstream Products

• 23851-46-9 bis(4-chlorophenyl)(hydroxy)acetic acid 
• 212852-47-6 3-[2,2-Bis-(4-chloro-phenyl)-2-hydroxy-acetylamino]-propionic acid 
• 34223-82-0 3,6-dichloro-9H-fluoren-9-one 

Relevant academic research and scientific papers

Physical, chemical, and isotopic (atomic) labels

Chemical or isotopic labels are added to, e.g., a potentially lethal drug formulation, to generate a unique chemical fingerprint. Combinations of chemical additives are mixed with the drug to aid in their isolation and identification, especially when such drugs are used for illicit purposes. When stable isotopes are incorporated into lethal drugs, the labeling process conveys a very unique internal chemical signature and greatly aids in the identification of the parent drug in body fluids and tissues. When heath-care providers become aware that certain drugs can now be easily tracked and identified in a victim, individuals may be reluctant to utilize these agents for ill purposes.

Dications of fluorenylidenes. The effect of substituent electronegativity and position on the antiaromaticity of substituted tetrabenzo[5.5]fulvalene dications

Oxidation of 3,6-disubstituted tetrabenzo[5.5]fulvalenes by SbF5 results in the formation of dications that behave like two antiaromatic fluorenyl cations connected by a single bond. Both fluorenyl systems exhibit the paratropic shifts and nucleus independent chemical shifts (NICS) characteristic of antiaromatic species. Comparison with analogous 2,7-disubstituted tetrabenzo[5.5]fulvalenes reveals that the antiaromaticity of the substituted ring system can be altered substantially by changes in the placement of the substituents, possibly due to changes in the delocalization of charge in the system. Substituents in the 3,6-position decrease the antiaromaticity because of the increase in the benzylic resonance compared to 2,7-substituents.

Macrocyclic plant acaricides

Compounds of the formula I STR1 in which either R is methyl and there is a double bond in the 9,10-position, or in which R is hydrogen and there is a single bond in the 9,10-position, are highly active against Acarina which damage plants.

Photoinduced Reaction : Part III - Photodegradation of p,p'-Dichlorodiphenyl-2,2,2-trichloroethanol (Dicofol), an Important Miticide

Dicofol (p,p'-dichlorodiphenyl-2,2,2-trichloroethanol) on photolysis undergoes a variety of changes involving addition of solvent radicals, reduction and oxidation.The degradation products have been isolated and characterised.In the solid state also it undergoes photodegradation to p,p'-dichlorobenzophenone (2).In alcoholic solution in the presence of radical quenchers like iodine and paraffin chlorobenzilic esters (6 and 9) are formed in high yields.Irridiation of dil. aqueous solution of 1 by sunlight brings about complete degradation to non-toxic products.Radical mechanism has been proposed for the formation of these products.

Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides

Various alkyl 4-[o-(substituted methyleneamino)phenyl]3-thioallophanates are useful as fungicides and mite ovicides. The compounds are prepared by reacting alkyl 4-(o-aminophenyl)-3-thioallophanates with aldehydes or trialkyl orthoformates. Some of the compounds are prepared by further reacting the reaction product of an alkyl 4-(o-aminophenyl)-3-thioallophanate and a trialkyl orthoformate with a primary or secondary amine. Exemplary species are methyl 4-[o-(o-fluorobenzylideneamino)phenyl]-3-thioallophanate, methyl 4-[o-(4-methylbenzylideneamino)phenyl]-3-thioallophanate and methyl 4-[o-(2-furfurylideneamino)phenyl]-3-thioallophanate.

Alkyl 4-[o-(substituted methyleneamino)phenyl]-3-thioallophanates

Various alkyl 4-[o-(substituted methyleneamino)phenyl] 3-thioallophanates are useful as fungicides and mite ovicides. The compounds are prepared by reacting alkyl 4-(o-aminophenyl)-3-thioallophanates with aldehydes or trialkyl orthoformates. Some of the compounds are prepared by further reacting the reaction product of an alkyl 4-(o-aminophenyl)-3-thioallophanate and a trialkyl orthoformate with a primary or secondary amine. Exemplary species are methyl 4-[o-(o-fluorobenzylideneamino)phenyl]-3-thioallophanate, methyl 4-[o-(4-methylbenzylideneamino)phenyl]-3-thioallophanate and methyl 4-[o-(2-furfurylideneamino)phenyl]-3-thioallophanate.

Pesticidal alkyl 4-(0-(substituted methyleneamine)-phenyl)-3-thioallophanates

Various alkyl 4-[o-(substituted methyleneamino)phenyl] 3-thioallophanates are useful as fungicides and mite ovicides. The compounds are prepared by reacting alkyl 4-(o-aminophenyl)-3-thioallophanates with aldehydes or trialkyl orthoformates. Some of the compounds are prepared by further reacting the reaction product of an alkyl 4-(o-aminophenyl)-3-thioallophanate and a trialkyl orthoformate with a primary or secondary amine. Exemplary species are methyl 4-[o-(o-fluorobenzylidine-amino)phenyl]-3-thioallophanate, methyl 4-[o-(4-methylbenzyl-ideneamino)phenyl]-3-thioallophanate and methyl 4-[o-(2-furfuryl-ideneamino)phenyl]-3-thioallophanate.