342906-16-5

Upstream product

• 181427-87-2 3-cyanomethyl-8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran 
• 149457-12-5 3-chloromethyl-8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran 
• 132971-59-6 8-hydroxy-3-hydroxymethyl-6-methoxyisocoumarin 
• 100-39-0 benzyl bromide 
• 181427-91-8 8-t-butyldimethylsilyloxy-3-cyanomethyl-6-methoxy-1-oxo-1H-2-benzopyran 

Relevant academic research and scientific papers

Synthesis and biological evaluation of cytogenin derivatives

To enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay.