34328-51-3Relevant academic research and scientific papers
Silver triflate/: P -TSA co-catalysed synthesis of 3-substituted isocoumarins from 2-alkynylbenzoates
Gianni, Jonathan,Pirovano, Valentina,Abbiati, Giorgio
, p. 3213 - 3219 (2018/05/17)
In this paper, we describe the silver triflate/p-toluenesulfonic acid co-catalysed synthesis of seventeen isocoumarins and two thieno[2,3-c]pyran-7-ones starting from 2-alkynylbenzoates and 3-alkynylthiophene-2-carboxylates, respectively. The reaction proceeds with absolute regioselectivity under mild reaction conditions and low catalyst loading, to afford the desired products in good to excellent yields. A conceivable reaction mechanism is proposed and supported by isotope-exchange tests, 1H NMR studies and ad hoc experiments.
Synthesis and characterization of 3-formyl-1H-2-benzopyran-1-one
Hussain, Mazhar,Ahmad, Hafiz Badaruddin,Shad, Muhammad Aslam,Hussain, Adeel,Shafiq, Zahid,Yousaf, Muhammad,Uzair, Muhammad
, p. 5473 - 5475,3 (2020/09/15)
Synthesis and characterization of 3-formyl-1H-2-benzopyran-1-one is reported through convenient three step method. Homophthalic acid and ethyloxalyl chloride were refluxed to afford isocoumarin 3-ethylcarboxylate, which was subsequently heated to reflux with ethanolic hydrazine hydrate to yield isocoumarin-3-hydrazide. The product is treated with ammoniacal solution of metaperiodate to synthesize 3-formyl-1H-2-benzopyran-1-one. All products were characterized by IR, NMR and mass spectral analysis. Physical and spectral data were in close agreement with those, reported in literature.
New Syntheses of trans-Artemidin, Artemidinal and Tetrahydrocapillarin
Chatterjea, J. N.,Mukherjee, Sanat K.,Bhakta, C.
, p. 359 - 361 (2007/10/02)
Convenient syntheses of the natural isocoumarins described in the title are reported starting from 3-bromomethylisocoumarin (2).Artemidinal (3) has been prepared in one step by subjecting 2 to Sommlet reaction. 3 on Perkin reaction using butyric anhydrid
